Morisset J
Service de gastroentérologie, department de medicine, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, Canada.
Adv Med Sci. 2008;53(2):99-118. doi: 10.2478/v10039-008-0029-5.
This review article has for major objective to summarize the old and latest developments on the hormonal controls of pancreatic growth. The article deals with hormonal controls during the fetal, neonatal and adult periods of pancreas development, growth and regeneration. During the fetal period, comparisons were made between studies performed with pancreatic explants and those designed in vivo. After birth, the effects of glucocorticoids, thyroxine, gastrin, bombesin, secretin, cholecystokinin alone or with secretin are reported. In the adults, similar studies were reported on hormones with addition of the effects of neuropeptides, the cell types targeted by hormones and the hormonal control after pancreatectomy and pancreatitis.
这篇综述文章的主要目的是总结胰腺生长激素调控方面的旧有及最新进展。文章探讨了胰腺发育、生长和再生的胎儿期、新生儿期及成年期的激素调控情况。在胎儿期，对胰腺外植体研究与体内设计研究进行了比较。出生后，报告了糖皮质激素、甲状腺素、胃泌素、蛙皮素、促胰液素、胆囊收缩素单独或与促胰液素联合使用的效果。在成年人中，报告了关于激素的类似研究，包括神经肽的作用、激素作用的细胞类型以及胰腺切除和胰腺炎后的激素调控。
