胰腺人生：个人经历

Life with the pancreas: A personal experience.

机构信息

Division of Gastroenterology, Department of Medicine, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001 12th Avenue North, Sherbrooke, Québec, J1H 5N4, Canada.

出版信息

Adv Med Sci. 2020 Mar;65(1):46-64. doi: 10.1016/j.advms.2019.11.002. Epub 2019 Dec 31.

DOI:10.1016/j.advms.2019.11.002

PMID:31901477

Abstract

This review article has primary objective to summarize pancreatic research which has been done in our laboratory since 1965, the first year of the author's registration in the Ph.D. program at the University of Sherbrooke (Canada). It covers the following major topics of pancreatic physiology: controls of pancreatic adaptation to diet, control of pancreatic enzyme secretion, control of pancreatic enzyme synthesis, control of pancreatic growth, intracellular events stimulated during pancreatic growth, pancreas regeneration after pancreatitis and pancreatectomy, the pancreatic cholecystokinin receptor types 1 and 2, growth control and cell signaling in pancreatic cancer cells and finally, cystic fibrosis.

摘要

这篇综述文章的主要目的是总结作者自 1965 年（即作者在加拿大舍布鲁克大学注册博士课程的第一年）以来在实验室进行的胰腺研究。它涵盖了以下胰腺生理学的主要主题：饮食对胰腺适应的控制、胰腺酶分泌的控制、胰腺酶合成的控制、胰腺生长的控制、胰腺生长过程中刺激的细胞内事件、胰腺炎和胰腺切除术后的胰腺再生、胰腺胆囊收缩素受体 1 型和 2 型、胰腺癌细胞的生长控制和细胞信号转导以及囊性纤维化。