Husek K, Zavadilová H, Cernoch J
II. patologicko-anatomický ústav LF MU, Brno.
Cesk Patol. 1991 Mar;27(1-2):26-32.
Aggressive angiomyxoma of pelvis and perineum was identified in two women (of 31 and 53). Its site was in the right fossa ischiorectalis and vulva. There was not observed any relaps in 60 and/or 9 months after surgery. Amorphous tumour mass was soft with finger-like projections. Spindle and starshaped tumour cells were spread in a loose edematous myxoid vascularized stroma; they had a benign character lacking of mitoses and nuclear atypia. Myxoid stroma could be stained rather faintly with Alcian blue at pH 1. Dilated capillaries, veins and arterioles were a substantial component of the tumour. Nerve and muscle fibres and their fragments were included here and there in the tumour. Tumour cells had a fibroblast ultrastructure which was supported by immunohistology. Discussion comprised differential diagnosis of myxoma, myxoid liposarcoma and myxoid type malignant fibrous histiocytoma among others.
两名女性(分别为31岁和53岁)被诊断出患有盆腔和会阴侵袭性血管黏液瘤。肿瘤位于右侧坐骨直肠窝和外阴。术后60个月和/或9个月未观察到任何复发情况。肿瘤呈无定形肿块,质地柔软,有指状突起。梭形和星形肿瘤细胞散布于疏松、水肿、黏液样、血管化的间质中;它们具有良性特征,无有丝分裂和核异型性。黏液样间质在pH 1的阿尔辛蓝染色下颜色较淡。扩张的毛细血管、静脉和小动脉是肿瘤的重要组成部分。肿瘤中散在分布着神经和肌肉纤维及其碎片。肿瘤细胞具有成纤维细胞超微结构,免疫组织学也证实了这一点。讨论内容包括黏液瘤、黏液样脂肪肉瘤和黏液样型恶性纤维组织细胞瘤等的鉴别诊断。