Cohen E J, Gonzalez C, Leavitt K G, Arentsen J J, Laibson P R
Cornea Service, Wills Eye Hospital, Philadelphia, PA 19107.
CLAO J. 1991 Jul;17(3):173-6.
We conducted a retrospective study of corneal ulcers that had been managed on the Cornea Service at Wills Eye Hospital in 1988 and 1989. Forty-four percent (51 of 116) of the ulcers were associated with contact lens use. Pseudomonas was the most often isolated organism (25 of 116, 22%) and was most frequently associated with cosmetic soft contact lenses (16 of 25, 64%). Ulcers associated with disposable contact lenses (five cases) were similar to those associated with conventional extended wear myopic lenses (15 cases). Pseudomonas was the predominant organism with both disposable (four of five, 80%) and conventional extended wear lenses (nine of 15, 60%). Staphylococcus aureus (19 cases) and Staphylococcus epidermidis (19 cases) were the next most frequently isolated organisms and usually occurred in ulcers not associated with contact lenses (29 of 38, 76%). Ulcers were treated 3.3 times more often in people using extended wear than in those using daily wear myopic lenses. Disposable contact lenses have not eliminated the problem of corneal ulcers associated with extended wear contact lenses.
我们对1988年和1989年在威尔斯眼科医院角膜科接受治疗的角膜溃疡进行了一项回顾性研究。44%（116例中的51例）的溃疡与隐形眼镜使用有关。铜绿假单胞菌是最常分离出的病原体（116例中的25例，占22%），且最常与美容软性隐形眼镜相关（25例中的16例，占64%）。与一次性隐形眼镜相关的溃疡（5例）与传统长戴型近视隐形眼镜相关的溃疡（15例）相似。铜绿假单胞菌是一次性隐形眼镜（5例中的4例，占80%）和传统长戴型隐形眼镜（15例中的9例，占60%）中的主要病原体。金黄色葡萄球菌（19例）和表皮葡萄球菌（19例）是其次最常分离出的病原体，通常发生在与隐形眼镜无关的溃疡中（38例中的29例，占76%）。与每日佩戴近视隐形眼镜的人相比，长戴型隐形眼镜使用者的溃疡治疗频率高出3.3倍。一次性隐形眼镜并未消除与长戴型隐形眼镜相关的角膜溃疡问题。
