García-March G, Sánchez-Ledesma M J, Broseta J
Servicio de Neurocirugía, Hospital Clínico Universitario, Valencia.
Neurocirugia (Astur). 2008 Oct;19(5):416-26.
The vagus nerve stimulation (VNS) therapy is a new neurostimulation technique used for treating pharmacoresistant epilepsy. It can be considered an effective and safe alternative for the treatment of refractory epilepsy patients. In the present review, we describe the surgical implantation technique, its indications and results achieved until now. We will also summarize the possible mechanisms of action of VNS therapy. Finally, we will comment on the difficulties and inconveniences that did not allow this antiepileptic surgical technique to become more widely used.
迷走神经刺激（VNS）疗法是一种用于治疗药物难治性癫痫的新型神经刺激技术。它可被视为治疗难治性癫痫患者的一种有效且安全的替代方法。在本综述中，我们描述了手术植入技术、其适应症以及迄今为止所取得的结果。我们还将总结VNS疗法可能的作用机制。最后，我们将对那些阻碍这种抗癫痫手术技术更广泛应用的困难和不便之处进行评论。
