Ghosh Sharda Brata, Tripathi Reva, Mala Y M, Khurana Nita
Department of Obstetrics, Gynaecology and Pathology, Maulana Azad Medical College, Lok Nayak Hospital, Delhi, 110002, India.
Arch Gynecol Obstet. 2009 Jan;279(1):91-3. doi: 10.1007/s00404-008-0815-0. Epub 2008 Oct 21.
Primary vaginal carcinoma associated with third degree uterovaginal prolapse is very rare.
We present a case report of a postmenopausal woman who presented with an invasive carcinoma of vagina associated with third degree uterovaginal prolapse treated by Mitra's operation. She was asymptomatic and had no recurrence during last 1 year of follow-up.
Vaginal ulcer associated with long standing genital prolapse need careful evaluation (including punch biopsy) for underlying carcinoma. Treatment due to the rarity of this entity was controversial previously and current review of literature suggests surgical treatment with or without radiotherapy as the optimum treatment for early stage and radiotherapy for advanced stage vaginal carcinoma associated with genital prolapse. Early diagnosis with adequate treatment can minimize the morbidity and mortality associated with vaginal carcinoma.
原发性阴道癌合并三度子宫阴道脱垂非常罕见。
我们报告一例绝经后女性病例，该患者患有与三度子宫阴道脱垂相关的浸润性阴道癌，接受了米特拉手术治疗。她无症状，在最后1年的随访中无复发。
与长期生殖器脱垂相关的阴道溃疡需要仔细评估（包括切取活检）以排查潜在癌症。由于该疾病罕见，其治疗方法以前存在争议，目前的文献综述表明，对于与生殖器脱垂相关的早期阴道癌，手术治疗加或不加放疗是最佳治疗方法，而晚期则采用放疗。早期诊断并给予适当治疗可将与阴道癌相关的发病率和死亡率降至最低。
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