Tailly Geert G, Baert Joost A, Hente K Robert, Tailly Thomas O
Departments of Urology, AZ KLINA, Brasshaat, Belgium.
J Endourol. 2008 Oct;22(10):2211-22. doi: 10.1089/end.2008.9706.
Since 1987 we have consecutively operated five different Dornier lithotriptors in the management of lithiasis at all levels of the urinary tract. At the time of usage of each machine we periodically evaluated the treatment results in order to eventually adapt treatment strategies to improve results. None of these evaluations comprised the totality of patients treated on a certain machine during the entire period it was in use. This overview retrospectively compares the results over the entire period in order to gauge the impact of the different machines and SW-sources on clinical results.
A total of 3079 patients, treated from september 1987 till september 2006 with two electrohydraulic machines, HM4 (1987-1988) and MPL9000 (1988-1994), and three electromagnetic machines, Compact (1991-1999), DoLi U/50 (1996-1999) and DoLi S (1999-2006) were thus evaluated. Parameters reviewed were stone location and size, retreatment rate, auxiliary procedures, stone free rate and Effectiveness Quotient (EQ).
There is no significant difference in stone size or stone free rate (p=0.4715) for the different groups. There is a significant difference for auxiliary procedure rate and retreatment rate for the different machines. The DoLiS with EMSE 220F-XXP scores significantly better than any of the other systems for auxiliary procedure rate pre-ESWL (p<0.05) and total auxiliary procedure rate (p<0.05), and retreatment rate (p=0.0024). There is a gradual increase in EQ with the consecutive machines.
Although stone free rates (85%-88.8%) remained constant, Effectiveness Quotients improved. This is largely due to reduced auxiliary procedure rates and reduced retreatment rates. The first effect is a consequence of improvement in treatment strategies and experience, the latter no doubt also of improvement in SW-sources.
自1987年以来,我们连续使用了五种不同的多尼尔碎石机来治疗尿路各级结石。在使用每台机器时,我们定期评估治疗结果,以便最终调整治疗策略以提高疗效。这些评估均未涵盖某台机器在其整个使用期间治疗的所有患者。本综述通过回顾性比较整个时期的结果,以评估不同机器和软件来源对临床结果的影响。
本研究共评估了1987年9月至2006年9月期间接受治疗的3079例患者,他们分别使用了两台液电式碎石机,即HM4(1987 - 1988年)和MPL9000(1988 - 1994年),以及三台电磁式碎石机,即Compact(1991 - 1999年)、DoLi U/50(1996 - 1999年)和DoLi S(1999 - 2006年)。回顾的参数包括结石位置、大小、再次治疗率、辅助治疗程序、结石清除率和有效率(EQ)。
不同组之间结石大小或结石清除率无显著差异(p = 0.4715)。不同机器的辅助治疗程序率和再次治疗率存在显著差异。配备EMSE 220F - XXP的DoLi S在ESWL前辅助治疗程序率(p < 0.05)、总辅助治疗程序率(p < 0.05)和再次治疗率(p = 0.0024)方面的表现明显优于其他任何系统。随着连续使用的机器不断更新,有效率逐渐提高。
尽管结石清除率(85% - 88.8%)保持不变,但有效率有所提高。这主要归因于辅助治疗程序率的降低和再次治疗率的降低。前者是治疗策略和经验改进的结果,后者无疑也是软件来源改进的结果。