Müller R, Weller P, Chemaissani A
Medizinische Klinik II und Poliklinik, Universität Köln.
Dtsch Med Wochenschr. 1991 Sep 20;116(38):1433-6. doi: 10.1055/s-2008-1063769.
A 58-year-old man was admitted to hospital because of exertional dyspnoea and a cardiac murmur not previously heard. For one year he was known to have left-sided fibrinous pleuritis. For 5 years he had been taking methysergide for cluster headaches. From 1950-1980 he had worked with asbestos-containing insulating material. Erythrocyte sedimentation rate was greatly increased to 117/136 mm and there was an hypochromic anaemia (Hb 10.4 g/dl). The cholestasis enzymes were elevated (gamma-GT 88 U/l; alkaline phosphatase 511 U/l). Computed tomography of the thorax demonstrated left-sided pleural thickening of up to 3 cm. Endocarditis was excluded (sterile blood culture; normal echocardiogram). There was no evidence of an infectious, immunological or malignant cause for the pleural fibrosis. One year after pleurectomy and having discontinued methysergide all biochemical tests were normal.
一名58岁男性因劳力性呼吸困难及此前未闻及的心杂音入院。已知他患有左侧纤维素性胸膜炎1年。他服用麦角新碱治疗丛集性头痛5年。1950年至1980年期间，他从事含石棉绝缘材料的工作。红细胞沉降率大幅升至117/136mm，存在低色素性贫血（血红蛋白10.4g/dl）。胆汁淤积酶升高（γ-谷氨酰转移酶88U/l；碱性磷酸酶511U/l）。胸部计算机断层扫描显示左侧胸膜增厚达3cm。排除了心内膜炎（血培养无菌；超声心动图正常）。没有证据表明胸膜纤维化存在感染、免疫或恶性病因。胸膜切除术后1年且停用麦角新碱后，所有生化检查均正常。
