Williams N
Department of Physiology, University of Melbourne, Parkville, Victoria, Australia.
Exp Hematol. 1991 Aug;19(7):714-8.
Recent data concerning to ability of interleukin 6 (IL-6) to stimulate platelet production have raised the possibility that platelet production is not specifically regulated by a unique feedback mechanism, but is part of a network encompassing several hemopoietic growth factors. Hypotheses are presented about the nature of thrombopoietin, its relationship to known growth factors, especially IL-6, and the specificity of a thrombopoietic response following change in the circulating platelet mass.
最近有关白细胞介素6（IL-6）刺激血小板生成能力的数据表明，血小板生成可能并非由独特的反馈机制特异性调节，而是包含多种造血生长因子的网络的一部分。文中提出了关于血小板生成素的性质、其与已知生长因子特别是IL-6的关系，以及循环血小板量变化后血小板生成反应特异性的假说。
