Terman A K
Fiziol Zh (1978). 1991 May-Jun;37(3):119-27.
An attempt is made to consider disease and aging following from the concepts of the essence of life. The proposed definition of life represents a modified Engels' (1878) definition. Proceeding from the analysis of possible mechanisms of different disturbances in the life process leading to a decreased probability of the organism existence it is concluded that disease develops either as a result of hereditary changes in the genome or due-to disorders in its realization under certain unfavorable conditions. Aging is determined by the properties of the genome itself and develops in connection with age increase.
本文尝试从生命本质的概念出发来思考疾病与衰老。所提出的生命定义沿用了恩格斯（1878年）的定义并有所 修改。通过分析生命过程中不同干扰因素导致生物体生存概率降低的可能机制，得出结论：疾病的发生要么是基因组遗传变化的结果，要么是在某些不利条件下其实现过程出现紊乱所致。衰老由基因组本身的特性决定，并随着年龄增长而出现。
