Sagach V F, Frol'kis I V, Kovalenko T N, Dibrova V A
Fiziol Zh (1978). 1991 May-Jun;37(3):36-43.
The experiments performed on isolated preparations of femoral artery and aorta of the mature and old rats as well as on those of coronary arteries of adult and old subjects failed to reveal direct participation of endothelium in the realization of insulin and vasopressin effects on the smooth muscles of the vessels studied. However, the endothelium modulated their influence on the vessels in the mature age. The lack of modulating effect of the endothelium in old age may be a result of its structural changes and thickening of a hemato-cellular barrier of the vessel wall observed by electron microscopy.
对成熟和老年大鼠的股动脉及主动脉分离标本，以及成年和老年受试者的冠状动脉标本所进行的实验未能揭示内皮在胰岛素和血管加压素对所研究血管平滑肌作用的实现过程中直接参与。然而，内皮在成年期调节了它们对血管的影响。老年期内皮缺乏调节作用可能是其结构变化以及通过电子显微镜观察到的血管壁血细胞屏障增厚的结果。
