Gurevich M I, Frol'kis I V
Biull Eksp Biol Med. 1983 Mar;95(3):11-3.
A study was made of the effects of insulin on smooth muscle cells (SMC) of the femoral artery of rats aged 6-8 and 24-26 months. Insulin hyperpolarized the SMC membrane and diminished the tone of smooth muscles of the vessels. These effects were dependent on the hormone concentration and perfusate temperature. In old animals, the sensitivity of smooth muscles of the vessels to insulin and the response to higher concentrations were reduced. It is believed that the changes described may play a definite role in the mechanisms by which the vascular tone is controlled.
对胰岛素对6 - 8月龄和24 - 26月龄大鼠股动脉平滑肌细胞（SMC）的影响进行了研究。胰岛素使SMC膜超极化，并降低血管平滑肌张力。这些作用取决于激素浓度和灌注液温度。在老年动物中，血管平滑肌对胰岛素的敏感性以及对较高浓度胰岛素的反应降低。据信，上述变化可能在控制血管张力的机制中起一定作用。
