Borodkin Adena F, Feigal Robert J, Beiraghi Soraya, Moller Karlind T, Hodges James S
School of Dentistry, University of Minnesota, Minneapolis, Minn, USA.
Pediatr Dent. 2008 Sep-Oct;30(5):408-13.
The purposes of this study were to: (1) quantify and compare permanent tooth development of cleft lip and palate (CLP) patients to age- and gender-matched controls; (2) relate these findings to cleft type and severity; and (3) examine delays in individual permanent maxillary teeth related to their proximity to the cleft.
Standardized methods using panoramic radiographs were employed to stage dental development and dental age for 49 children with clefts and 49 matched controls. Data were analyzed with a mixed linear model.
Analyses indicated a correlation between delayed permanent tooth development and CLP with an overall delay of 0.52 years (P = .02) and with boys accounting for all the delay. No differences were found between subjects with unilateral or bilateral clefts. A nonsignificant trend was noted for greater delay in subjects with clefts of the primary and secondary palates vs primary palate alone. Teeth most often affected by the delay were maxillary first and second premolars and maxillary second molars.
While permanent tooth development is delayed in cleft lip and palate patients, this delay is: found in boys only; is independent of the cleft type and severity; and is not correlated with proximity to the cleft.
本研究的目的是:(1)对唇腭裂(CLP)患者的恒牙发育情况进行量化,并与年龄和性别匹配的对照组进行比较;(2)将这些结果与腭裂类型和严重程度相关联;(3)研究单个上颌恒牙的发育延迟与其与腭裂的距离之间的关系。
采用标准化方法,利用全景X线片对49例腭裂患儿和49例匹配的对照者进行牙齿发育分期和牙龄评估。数据采用混合线性模型进行分析。
分析表明,恒牙发育延迟与唇腭裂之间存在相关性,总体延迟0.52年(P = 0.02),且延迟全部由男孩造成。单侧或双侧腭裂患者之间未发现差异。与仅为原发腭腭裂的患者相比,原发腭和继发腭腭裂患者的延迟趋势更为明显,但差异无统计学意义。最常受延迟影响的牙齿是上颌第一和第二前磨牙以及上颌第二磨牙。
虽然唇腭裂患者的恒牙发育延迟,但这种延迟仅见于男孩;与腭裂类型和严重程度无关;且与距腭裂的距离无关。