Department of Orthodontics, University Hospital Tübingen, Osianderstr. 2-8, 72076, Tubingen, Germany.
Department of Oral and Maxillofacial Surgery, University Hospital Tübingen, Osianderstr. 2-8, 72076, Tubingen, Germany.
Clin Oral Investig. 2022 Sep;26(9):5823-5832. doi: 10.1007/s00784-022-04538-2. Epub 2022 May 26.
The study objective was to evaluate the tooth agenesis in German orthodontic patients with non-syndromic cleft lip and/or palate and Robin sequence compared to a control group without craniofacial disorder.
MATERIALS/METHODS: A total of 108 panoramic radiographs were examined using the binary system of Tooth Agenesis Code (TAC) (excluding the third molar). Patients were divided into the craniofacial disorder group 1 (n = 43) and the healthy control group 2 (n = 65). Parameters such as skeletal class malformation, sex, localization of the cleft, craniofacial disorder, and interobserver reliability were assessed.
Permanent tooth agenesis was observed in 44% of group 1 and 14% in group 2 with a statistically significant higher prevalence (p = 0.00162 (χ)). Fourteen different TAC patterns were observed in group 1, ten of these occurring only once in separate patients. The distribution of the TAC codes in group 2 showed nine different possibilities of TAC code patterns; seven TACs were unique. In group 1, the most frequently absent teeth were the maxillary lateral incisor of the left side (30%); in group 2, the second premolar of the lower jaw on the right side (9%). Male patients with craniofacial disorder showed a higher percentage of tooth agenesis than female.
The data presented here shows a statistically significant higher prevalence of tooth agenesis in German patients with non-syndromic craniofacial disorder.
Radiographic evaluation enables the diagnosis of tooth agenesis. Recognizing early on the higher prevalence of tooth agenesis in patients exhibiting a craniofacial disorder is an important issue when developing long-term and comprehensive interdisciplinary treatment.
本研究旨在评估非综合征型唇腭裂和/或Robin 序列患者的恒牙缺失情况，并与无颅面畸形的对照组进行比较。
材料/方法：共检查了 108 张全景片，采用恒牙缺失编码（TAC）的二进制系统（不包括第三磨牙）。患者分为颅面畸形组 1（n=43）和健康对照组 2（n=65）。评估了骨骼畸形程度、性别、裂隙位置、颅面畸形等参数，并评估了观察者间的可靠性。
组 1 中永久性恒牙缺失率为 44%，组 2 为 14%，差异具有统计学意义（p=0.00162（χ2））。组 1 观察到 14 种不同的 TAC 模式，其中 10 种仅在个别患者中出现过一次。组 2 的 TAC 码分布显示了 9 种不同的 TAC 码模式，其中 7 种是唯一的。在组 1 中，最常缺失的牙齿是左侧上颌侧切牙（30%）；在组 2 中，右侧下颌第二磨牙（9%）。有颅面畸形的男性患者的恒牙缺失率高于女性。
这里提供的数据显示，德国非综合征型颅面畸形患者恒牙缺失的发生率具有统计学意义。
影像学评估可诊断恒牙缺失。在制定长期、全面的跨学科治疗方案时，早期认识到存在颅面畸形的患者恒牙缺失率较高是非常重要的。
