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脉冲电磁场治疗慢性静脉曲张性溃疡:一项对照性初步研究。

Treatment of chronic varicose ulcers with pulsed electromagnetic fields: a controlled pilot study.

作者信息

Todd D J, Heylings D J, Allen G E, McMillin W P

机构信息

Department of Dermatology, Belfast City Hospital.

出版信息

Ir Med J. 1991 Jun;84(2):54-5.

PMID:1894496
Abstract

To evaluate the efficacy of pulsed electromagnetic fields (PEMF) in healing of chronic varicose ulcers, 19 patients with this condition were included in a double-blind controlled clinical trial. All patients received standard ulcer therapy throughout the duration of the study and were randomly divided into two groups to receive either active or inactive PEMF therapy. Active therapy was provided by the use of a pait of helmholtz coils on a twice weekly basis over a five week period and inactive therapy was provided on an identical regimen with identical coils wound so that no magnetic field was produced when an electric current was passed through them. The clinician and patients were unable to distinguish the active or inactive coils. No statistically relevant difference was noted between the two groups in the healing rates of the ulcer, change in the lower leg girth, pain or infection rates. However there was a trend in favour of a decrease in ulcer size and lower leg girth in the group treated with active PEMF. As PEMF is a novel treatment for chronic varicose ulcers, more work needs to be done to establish treatment parameters and its usefulness in the treatment of this condition.

摘要

为评估脉冲电磁场(PEMF)对慢性静脉曲张性溃疡愈合的疗效,19例患有该疾病的患者被纳入一项双盲对照临床试验。在整个研究期间,所有患者均接受标准溃疡治疗,并被随机分为两组,分别接受有源或无源PEMF治疗。有源治疗是通过使用一对亥姆霍兹线圈,每周两次,持续五周进行的;无源治疗则采用相同的方案,使用相同的线圈缠绕,使得当电流通过时不会产生磁场。临床医生和患者均无法区分有源或无源线圈。两组在溃疡愈合率、小腿周长变化、疼痛或感染率方面均未发现统计学上的显著差异。然而,接受有源PEMF治疗的组中,溃疡大小和小腿周长有减小的趋势。由于PEMF是治疗慢性静脉曲张性溃疡的一种新型疗法,需要开展更多工作来确定治疗参数及其在治疗该疾病中的有效性。

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