Jeffery A K, Blunn G W, Archer C W, Bentley G
University of Otago, Dunedin, New Zealand.
J Bone Joint Surg Br. 1991 Sep;73(5):795-801. doi: 10.1302/0301-620X.73B5.1894669.
The three-dimensional architecture of bovine articular cartilage collagen and its relationship to split lines has been studied with scanning electron microscopy. In the middle and superficial zones, collagen was organised in a layered or leaf-like manner. The orientation was vertical in the intermediate zone, curving to become horizontal and parallel to the articular surface in the superficial zone. Each leaf consisted of a fine network of collagen fibrils. Adjacent leaves merged or were closely linked by bridging fibrils and were arranged according to the split-line pattern. The surface layer (lamina splendens) was morphologically distinct. Although ordered, the overall collagen structure was different in each plane (anisotropic) a property described in previous morphological and biophysical studies. As all components of the articular cartilage matrix interact closely, the three-dimensional organisation of collagen is important when considering cartilage function and the processes of cartilage growth, injury and repair.
利用扫描电子显微镜研究了牛关节软骨胶原蛋白的三维结构及其与劈裂线的关系。在中间区和表层区，胶原蛋白呈层状或叶状排列。在中间区，其取向是垂直的，在表层区则弯曲成水平并与关节表面平行。每片叶由精细的胶原纤维网络组成。相邻的叶通过桥接纤维融合或紧密相连，并按照劈裂线模式排列。表面层（光彩层）在形态上是独特的。尽管有序，但各平面的整体胶原蛋白结构不同（各向异性），这一特性在以前的形态学和生物物理学研究中已有描述。由于关节软骨基质的所有成分都密切相互作用，因此在考虑软骨功能以及软骨生长、损伤和修复过程时，胶原蛋白的三维组织很重要。
