Huang Chin-Sung, Wu Wei-Fong
Department of Pediatrics, Taipei City Hospital Ren-Ai Branch, Taipei, Taiwan.
Pediatr Neonatol. 2008 Apr;49(2):35-8. doi: 10.1016/S1875-9572(08)60009-1.
Only a few cases of hypertriglyceridemia in patients with systemic lupus erythematosus (SLE) have been reported. We report a case of a 13-year-old girl suffering from SLE associated with severe hypertriglyceridemia. The persistent hypertriglyceridemia was extremely well tolerated. As a result of steroid treatment, serum triglycerides fell dramatically from a high of 5601 mg/dL to 75 mg/dL despite the patient switching to a free diet. We considered the presence of an autoantibody to lipoprotein lipase and commenced immunosuppression. The role of steroids in completely correcting deficient lipoprotein lipase activity is discussed.
