Yao Jian-Min, Zhao Xiang-Dong, Xiao Zhi-Bin, Lu Ning, Lu Long, Pang Zhong-Yi, Wang Dong-Wen, Cui Zhen-Tian, Liu Jing
Department of Cardiovascular Surgery, Heart Center, General Hospital of Beijing Military Region, People's Liberation Army, Beijing 100700, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2008 Oct;10(5):596-8.
To report the experience of the surgical treatment of congenital heart diseases (CHD) in pediatric patients with body weight less than 10 kg.
Between January 2000 and December 2007, 105 children with CHD, aged 2 months to 3 years and weighing between 3.5 to 10 kg, underwent surgical treatment. Of the 105 patients, 56 were concomitant with moderate to severe pulmonary hypertension or repeated pulmonary infections, and 35 with complex cardiac abnormalities. Operations were performed through median sternotomy with moderate hypothermic cardiopulmonary bypass in 88 cases, with normothermic extracorporeal circulation on beating heart in 14 cases, and with deep hypothermic circulatory arrest in 3 cases.
There were 5 early deaths (4.8%). During a follow-up of 2 month to 3 year, 97 survivors with corrective procedure had no late mortality or complications with NYHA class I of cardiac function, excepting 2 cases with little residual shunt. Three survivors with palliative procedure enjoyed higher quality of life.
The surgical treatment of CHD in pediatric patients with body weight less than 10 kg seems to be feasible and safe, with satisfactory early and long-term results.
报告体重小于10kg的小儿先天性心脏病（CHD）的外科治疗经验。
2000年1月至2007年12月，105例年龄2个月至3岁、体重3.5至10kg的CHD患儿接受了外科治疗。105例患者中，56例合并中度至重度肺动脉高压或反复肺部感染，35例合并复杂心脏畸形。88例通过正中胸骨切开术并采用中度低温体外循环进行手术，14例在心脏跳动下采用常温体外循环，3例采用深低温停循环。
早期死亡5例（4.8%）。在2个月至3年的随访中，97例接受矫治手术的幸存者无晚期死亡或并发症，心功能纽约心脏协会（NYHA）分级为I级，除2例有少量残余分流。3例接受姑息手术的幸存者生活质量较高。
体重小于10kg的小儿CHD外科治疗似乎可行且安全，早期和长期效果良好。
