Friedman D B, Hashimoto K
Department of Dermatology and Syphilogy, Wayne State University School of Medicine, Detroit, MI 48201.
J Am Acad Dermatol. 1991 Aug;25(2 Pt 2):392-4. doi: 10.1016/0190-9622(91)70212-k.
We describe a case of generalized, asymptomatic, chronic annular lichen planus. The centers of the large annular lesions were atrophic and had lost their elasticity. Histologic examination revealed an absence of elastic fiber in the center. Electron microscopy revealed fragmented elastic fibers. Examination of early lesions showed that elastolysis had already begun in the heavy cellular infiltration. We conclude that the annular configuration resulted from the elastolytic activity of the inflammatory cells with the formation of foci of localized acquired cutis laxa.
我们描述了一例全身性、无症状的慢性环状扁平苔藓病例。大的环状皮损中心萎缩且失去弹性。组织学检查显示中心部位缺乏弹性纤维。电子显微镜检查发现弹性纤维断裂。对早期皮损的检查表明,在大量细胞浸润处弹性纤维溶解已经开始。我们得出结论,环状形态是由炎症细胞的弹性纤维溶解活性导致局部获得性皮肤松弛灶形成所致。