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表现为第三脑室肿块及梗阻性脑积水的基底动脉尖部动脉瘤——病例报告——

Basilar apex aneurysm manifesting as third ventricular mass and obstructive hydrocephalus--case report--.

作者信息

Tsutsumi Satoshi, Kondo Akihide, Abe Yusuke, Yasumoto Yukimasa, Ito Masanori

机构信息

Department of Neurological Surgery, Juntendo University Urayasu Hospital, Urayasu, Chiba, Japan.

出版信息

Neurol Med Chir (Tokyo). 2008 Oct;48(10):451-4. doi: 10.2176/nmc.48.451.

Abstract

A 58-year-old male, with a past history of hypertensive thalamic hemorrhage 12 years before, presented with gradually exaggerating gait disturbance, memory disturbance, and urinary incontinence. On admission, he had gait disturbance represented by petit pas and anteropulsion in addition to significant recent memory disturbance. Cranial computed tomography (CT) revealed a hyperdense mass in the third ventricle with triventricular dilation. Cerebral magnetic resonance (MR) imaging and MR angiography identified the third ventricular lesion as saccular basilar apex aneurysm. No other intracranial abnormal intensity contributing to his clinical symptoms was recognized. Cervical MR angiography showed normal findings. Cerebral blood flow (CBF) measurements revealed diffuse CBF reduction in the cerebral hemisphere. The patient underwent coil embolization which accomplished complete aneurysm occlusion. He showed only slight improvement in his gait disturbance after embolization, and CT following embolization revealed persistent ventriculomegaly. Ventriculoperitoneal shunting was carried out. Intraoperative neuroendoscopy demonstrated cerebrospinal fluid (CSF) obstruction caused by the embolized aneurysm at the level of the third ventricle, with normal CSF findings. Postoperatively his gait disturbance and intellectual impairment showed remarkable improvement. Basilar apex aneurysm associated with obstructive hydrocephalus has complex underlying pathology and should be treated by a combination of definitive aneurysm obliteration and CSF diversion.

摘要

一名58岁男性,12年前有高血压性丘脑出血病史,现出现逐渐加重的步态障碍、记忆障碍和尿失禁。入院时,除了近期明显的记忆障碍外,他还存在以小步和前冲步态为特征的步态障碍。头颅计算机断层扫描(CT)显示第三脑室内有高密度肿块,伴有三脑室扩张。脑部磁共振成像(MR)及磁共振血管造影(MRA)确定第三脑室病变为囊状基底动脉尖动脉瘤。未发现其他导致其临床症状的颅内异常信号。颈部MRA显示正常。脑血流量(CBF)测量显示大脑半球CBF弥漫性减少。患者接受了弹簧圈栓塞治疗,动脉瘤完全闭塞。栓塞后其步态障碍仅略有改善,栓塞后CT显示脑室持续扩大。遂行脑室腹腔分流术。术中神经内镜检查显示第三脑室水平栓塞的动脉瘤导致脑脊液(CSF)梗阻,CSF检查结果正常。术后其步态障碍和智力损害明显改善。基底动脉尖动脉瘤合并梗阻性脑积水有复杂的潜在病理机制,应采用确定性动脉瘤闭塞和CSF分流相结合的方法进行治疗。

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