Suau C Thelma, Piñera M Cecilia, Díaz W Sergio, Troncoso R Esteban
Departamento de Pediatría y Cirugía Infantil Sur, Universidad de Chile, Santiago, Chile.
Rev Chilena Infectol. 2008 Oct;25(5):374-8. Epub 2008 Oct 1.
Outpatient parenteral antimicrobial therapy (OPAT) was first introduced in 1973 as an alternative treatment. Since then, there have been numerous international case based studies including both children and adults with significant bacterial infections using this strategy. The protocol requires a careful screening and evaluation process of the patient. There must be no other motive for hospitalization other than the need for parenteral antibiotics.
To describe the results of OPAT during a period of 26 months in emergency department of a Chilean pediatric public hospital.
During the study period 228,144 patients received medical care in the Emergency Department (ED) and 380 patients were admitted to the OPAT program after clinical evaluation and based on the socioeconomic and cultural conditions of their parents. The major indications of OPAT were skin and soft tissues infections (50%) and pneumonia (28%) respectively. (beta-lactamic antibiotics the were most commonly prescribed. Thirty eight patients (10%) required hospitalization, mostly because of clinical deterioration. There were no deaths.
In our public hospital OPAT for treatment of significant bacterial infections constitutes an efficient and safe alternative to hospitalization allowing the child to remain in his home.
门诊胃肠外抗菌治疗（OPAT）于1973年首次作为一种替代治疗方法引入。从那时起，有许多基于国际病例的研究，涉及使用该策略治疗严重细菌感染的儿童和成人。该方案要求对患者进行仔细的筛查和评估过程。除了需要胃肠外使用抗生素外，不得有其他住院的动机。
描述智利一家儿科公立医院急诊科在26个月期间的门诊胃肠外抗菌治疗（OPAT）结果。
在研究期间，228144名患者在急诊科接受了医疗护理，380名患者在经过临床评估并根据其父母的社会经济和文化状况后被纳入OPAT项目。OPAT的主要适应症分别为皮肤和软组织感染（50%）和肺炎（28%）。最常开具的是β-内酰胺类抗生素。38名患者（10%）需要住院治疗，主要是因为临床病情恶化。无死亡病例。
在我们的公立医院，门诊胃肠外抗菌治疗（OPAT）用于治疗严重细菌感染是一种有效且安全的替代住院治疗的方法，可让儿童留在家里。
