一名青少年蕈样肉芽肿伴局灶性CD30转化。

Mycosis fungoides with focal CD 30 transformation in an adolescent.

作者信息

Romero Monica, Haney Michaela, Desantis Emily, Zlotoff Barrett

机构信息

Department of Dermatology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.

出版信息

Pediatr Dermatol. 2008 Sep-Oct;25(5):565-8. doi: 10.1111/j.1525-1470.2008.00763.x.

DOI:10.1111/j.1525-1470.2008.00763.x

PMID:18950403

Abstract

Mycosis fungoides is rare in children and adolescents. Large cell transformation in mycosis fungoides is typically seen in adult patients with advanced disease. We describe a 16-year-old girl with patch/plaque stage mycosis fungoides who developed a nodule within one of the plaques, which on histopathology showed large cell transformation, with positive labeling with the CD30 immunostain. To the best of our knowledge, this is the second reported case of mycosis fungoides with CD30+ large cell transformation in a child.

摘要

蕈样肉芽肿在儿童和青少年中较为罕见。蕈样肉芽肿的大细胞转化通常见于患有晚期疾病的成年患者。我们描述了一名16岁患有斑块期蕈样肉芽肿的女孩，其在其中一个斑块内出现了一个结节，组织病理学显示为大细胞转化，CD30免疫染色呈阳性。据我们所知，这是第二例报道的儿童蕈样肉芽肿伴CD30 +大细胞转化的病例。