猪到灵长类动物异种移植中当前的细胞免疫障碍。
Current cellular immunological hurdles in pig-to-primate xenotransplantation.
作者信息
Le Bas-Bernardet Stéphanie, Blancho Gilles
机构信息
INSERM, U643, Nantes, France.
出版信息
Transpl Immunol. 2009 Jun;21(2):60-4. doi: 10.1016/j.trim.2008.10.006. Epub 2008 Oct 24.
PMID:18952170
Abstract
In this review, we summarize the work published over the last few years relative to cellular immunological hurdles encountered specifically in pig-to-primate xenotransplantation models. The works summarized here cover both the innate and adaptative cellular immune response as well as strategies to overcome them and consequently prevent xenograft rejection.
摘要
在本综述中，我们总结了过去几年发表的有关在猪到灵长类动物异种移植模型中特别遇到的细胞免疫障碍的研究工作。这里总结的研究工作涵盖了先天性和适应性细胞免疫反应，以及克服这些反应从而预防异种移植物排斥的策略。
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