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幽门螺杆菌G27菌株的全基因组序列

The complete genome sequence of Helicobacter pylori strain G27.

作者信息

Baltrus David A, Amieva Manuel R, Covacci Antonello, Lowe Todd M, Merrell D Scott, Ottemann Karen M, Stein Markus, Salama Nina R, Guillemin Karen

机构信息

Department of Biology, University of Carolina at Chapel Hill, Chapel Hill, NC 27599-3280, USA.

出版信息

J Bacteriol. 2009 Jan;191(1):447-8. doi: 10.1128/JB.01416-08. Epub 2008 Oct 24.

DOI:10.1128/JB.01416-08
PMID:18952803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2612421/
Abstract

Helicobacter pylori is a gram-negative pathogen that colonizes the stomachs of over half the world's population and causes a spectrum of gastric diseases including gastritis, ulcers, and gastric carcinoma. The H. pylori species exhibits unusually high levels of genetic variation between strains. Here we announce the complete genome sequence of H. pylori strain G27, which has been used extensively in H. pylori research.

摘要

幽门螺杆菌是一种革兰氏阴性病原体,它定植于全球超过一半人口的胃部,并引发一系列胃部疾病,包括胃炎、溃疡和胃癌。幽门螺杆菌菌株之间表现出异常高水平的遗传变异。在此,我们公布幽门螺杆菌G27菌株的完整基因组序列,该菌株已在幽门螺杆菌研究中广泛使用。

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本文引用的文献

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Natural transformation increases the rate of adaptation in the human pathogen Helicobacter pylori.自然转化提高了人类病原体幽门螺杆菌的适应率。
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Identification of Helicobacter pylori genes that contribute to stomach colonization.鉴定有助于在胃部定殖的幽门螺杆菌基因。
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The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression.一株慢性萎缩性胃炎幽门螺杆菌菌株的全基因组序列:疾病进展过程中的进化
Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9999-10004. doi: 10.1073/pnas.0603784103. Epub 2006 Jun 20.
5
Phosphorylation-independent effects of CagA during interaction between Helicobacter pylori and T84 polarized monolayers.幽门螺杆菌与T84极化单层细胞相互作用期间CagA的非磷酸化依赖性效应
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Science. 2003 May 30;300(5624):1430-4. doi: 10.1126/science.1081919.
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