幽门螺杆菌G27菌株的全基因组序列
The complete genome sequence of Helicobacter pylori strain G27.
作者信息
Baltrus David A, Amieva Manuel R, Covacci Antonello, Lowe Todd M, Merrell D Scott, Ottemann Karen M, Stein Markus, Salama Nina R, Guillemin Karen
机构信息
Department of Biology, University of Carolina at Chapel Hill, Chapel Hill, NC 27599-3280, USA.
出版信息
J Bacteriol. 2009 Jan;191(1):447-8. doi: 10.1128/JB.01416-08. Epub 2008 Oct 24.
Abstract
Helicobacter pylori is a gram-negative pathogen that colonizes the stomachs of over half the world's population and causes a spectrum of gastric diseases including gastritis, ulcers, and gastric carcinoma. The H. pylori species exhibits unusually high levels of genetic variation between strains. Here we announce the complete genome sequence of H. pylori strain G27, which has been used extensively in H. pylori research.
摘要
幽门螺杆菌是一种革兰氏阴性病原体，它定植于全球超过一半人口的胃部，并引发一系列胃部疾病，包括胃炎、溃疡和胃癌。幽门螺杆菌菌株之间表现出异常高水平的遗传变异。在此，我们公布幽门螺杆菌G27菌株的完整基因组序列，该菌株已在幽门螺杆菌研究中广泛使用。
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