大鼠肝脏和莫里斯肝癌的组蛋白及核磷蛋白研究。
Studies on histones and nuclear phosphoproteins of rat liver and Morris hepatoma.
作者信息
Lipińska A, Krajewska W, Kiliańska Z, Wierzbicki R, Klyszejko-Stefanowicz L
出版信息
Acta Biochim Pol. 1976;23(4):335-40.
PMID:189536
Abstract
- The chemical composition of chromatins obtained from Buffalo rat liver and Morris hepatoma strain 5123 was investigated. 2. The presence of an additional subfraction within the very lysine-rich histone (fl) was states in both kinds of tissues. It amounted to about 8% and 5% of fl in rat liver and Morris hepatoma, respectively. 3. Nuclear phosphoproteins (phenol-soluble) from normal and tumour tissues in polyacrylamide gel in SDS showed some qualitative differences in the range of molecular weights of about 40 000 - 70 000 and over 100 000 daltons.
摘要
- 对从水牛大鼠肝脏和莫里斯肝癌5123株中获得的染色质的化学成分进行了研究。2. 在这两种组织中均发现富含赖氨酸的组蛋白（f1）内存在一个额外的亚组分。在大鼠肝脏和莫里斯肝癌中，该亚组分分别占f1的约8%和5%。3. 正常组织和肿瘤组织中的核磷蛋白（酚溶性）在SDS聚丙烯酰胺凝胶中显示，在分子量约40000 - 70000以及超过100000道尔顿的范围内存在一些定性差异。
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