Hei Yan, Kang Li, Li Yue-yue, Xiao Li-hua
Institute of Orbital Diseases, Armed Police General Hospital, Beijing 100039, China.
Zhonghua Yan Ke Za Zhi. 2008 May;44(5):423-6.
To study the morphological representation of the orbital tissue in thyroid associated ophthalmopathy.
It was a retrospective case series. 138 specimens of TAO (include 77 specimens of orbital fat, 41 specimens of orbital periosteum and 20 specimens of lacrimal gland tissue) were analyzed by light microscopy and immunohistochemical staining.
The notable hyperplasia of fat was found in orbital tissue from 73 of 77 and in lacrimal gland tissue from 12 of 20. The hyperplasia of fibrous tissue and muscular metaplasia were observed in orbital periosteum.
The hyperplasia of fat in TAO orbital and lacrimal gland tissue is a very important and ubiquitous pathological changes. Study on the orbital fat and prevent against the hyperplasia of fat maybe have a significance of effective to hold back proptosis.
研究甲状腺相关眼病眼眶组织的形态学表现。
这是一项回顾性病例系列研究。对138例甲状腺相关眼病标本（包括77例眼眶脂肪标本、41例眼眶骨膜标本和20例泪腺组织标本）进行了光学显微镜检查和免疫组织化学染色分析。
77例眼眶组织中有73例出现明显的脂肪增生，20例泪腺组织中有12例出现脂肪增生。在眼眶骨膜中观察到纤维组织增生和肌肉化生。
甲状腺相关眼病眼眶和泪腺组织中的脂肪增生是一种非常重要且普遍存在的病理变化。对眼眶脂肪进行研究并预防脂肪增生可能对抑制眼球突出具有有效意义。
