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通过间接测热法评估健康受试者和肝硬化患者的能量消耗。

Assessment of energy expenditure by indirect calorimetry in healthy subjects and patients with liver cirrhosis.

作者信息

Vermeij C G, Feenstra B W, Oomen A M, de Graaf E J, Zillikens M C, Swart G R, Bruining H A

机构信息

Department of General Surgery, University Hospital Dijkzigt, Rotterdam, The Netherlands.

出版信息

JPEN J Parenter Enteral Nutr. 1991 Jul-Aug;15(4):421-5. doi: 10.1177/0148607191015004421.

DOI:10.1177/0148607191015004421
PMID:1895487
Abstract

The reliability of resting energy expenditure (REE) measurements by indirect calorimetry with a ventilated hood was investigated in 50 healthy controls and 10 patients with liver cirrhosis. In each subject basal energy expenditure (BEE) was determined once and REE three times (morning REE1, noon REE2, afternoon REE3). In controls and patients the first 5-minute BEE and first 5-minute REE (controls also second 5-minute REE) were higher than in the remainder of the 30-minute recording. Only the last 20 minutes of recordings were used to calculate BEE (1645 +/- 315, mean +/- SD, in kilocalories per day), REE1 (1880 +/- 365), REE2 (1782 +/- 384), and REE3 (1775 +/- 316) in controls, and in cirrhotics: BEE (1530 +/- 235), REE1 (1714 +/- 267), REE2 (1715 +/- 238), and REE3 (1779 +/- 275). REE was higher than BEE in controls and cirrhotics (p less than 0.05). The REE variation coefficient was 5 +/- 3% in controls and 5 +/- 2% in cirrhotics. No systematic difference between REE1, REE2, and REE3 was found. Energy expenditure predicted by the Harris-Benedict equation differed up to 21% from measured BEE in individual controls; group mean BEE, however, was correctly predicted. In cirrhotics differences between measured and predicted BEE up to 26% occurred, while measured BEE was higher than predicted BEE (p = 0.06). It is concluded that REE can be reliably assessed by indirect calorimetry with a ventilated hood system in controls and patients at any time of the day, when values obtained in the first 10 minutes are deleted.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

采用带通风罩的间接测热法对50名健康对照者和10名肝硬化患者静息能量消耗(REE)测量的可靠性进行了研究。对每个受试者测定一次基础能量消耗(BEE),REE测定三次(早晨REE1、中午REE2、下午REE3)。在对照者和患者中,最初5分钟的BEE和最初5分钟的REE(对照者还有第二个5分钟的REE)高于30分钟记录的其余部分。仅使用记录的最后20分钟来计算对照者的BEE(1645±315,均值±标准差,千卡/天)、REE1(1880±365)、REE2(1782±384)和REE3(1775±316),以及肝硬化患者的BEE(1530±235)、REE1(1714±267)、REE2(1715±238)和REE3(1779±275)。对照者和肝硬化患者的REE均高于BEE(p<0.05)。对照者的REE变异系数为5±3%,肝硬化患者为5±2%。未发现REE1、REE2和REE3之间存在系统性差异。在个体对照者中,哈里斯-本尼迪克特方程预测的能量消耗与测得的BEE相差高达21%;然而,组均值BEE得到了正确预测。在肝硬化患者中,测得的BEE与预测的BEE之间的差异高达26%,而测得的BEE高于预测的BEE(p = 0.06)。结论是,当删除前10分钟获得的值时,带通风罩系统的间接测热法可在一天中的任何时间对对照者和患者的REE进行可靠评估。(摘要截取自250字)

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Are Predictive Energy Expenditure Equations Accurate in Cirrhosis?预测能量消耗方程在肝硬化中准确吗?
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