Waluga M, Zahorska-Markiewicz B, Janusz M, Słabiak Z, Chełmicka A
Department of Gastroenterology, Silesian Medical Academy, Katowice, Poland.
Experientia. 1996 Jun 15;52(6):591-6. doi: 10.1007/BF01969735.
Energy expenditure was investigated in 15 patients with liver cirrhosis and 20 healthy controls by three methods: indirect calorimetry, anthropometry using the Harris-Benedict equation and bioelectrical impedance analysis. The energy expenditure was expressed in kcal/day, kcal/kg BW/day (BW - body weight), kcal/kg LBM/day (LBM - lean body mass, derived by bioelectrical impedance analysis) or in kcal/m2/day. We did not find statistical differences between values of resting energy expenditure obtained in patients with cirrhosis of the liver and healthy controls whichever method we used. We also did not find statistical differences between values obtained by indirect calorimetry, anthropometry and bioelectrical impedance analysis. There was a significant correlation between indirect calorimetry and anthropometry in both groups. We found significant correlations between indirect calorimetry and anthropometry, and between indirect calorimetry and bioelectrical impedance analysis, in the control group only. We can conclude that (1) resting energy expenditure of patients with cirrhosis of the liver is not changed when compared with healthy controls, and (2) bioelectrical impedance is a useful method to calculate body composition from which energy expenditure is derived; however, it gives an appropriate result only in healthy people, and only approximate values in patients with cirrhosis.
采用间接测热法、运用哈里斯-本尼迪克特方程的人体测量法以及生物电阻抗分析法这三种方法，对15例肝硬化患者和20名健康对照者的能量消耗进行了研究。能量消耗以千卡/天、千卡/千克体重/天（BW-体重）、千卡/千克去脂体重/天（LBM-去脂体重，通过生物电阻抗分析得出）或千卡/平方米/天来表示。无论采用哪种方法，我们都未发现肝硬化患者和健康对照者的静息能量消耗值之间存在统计学差异。我们也未发现间接测热法、人体测量法和生物电阻抗分析法所测得的值之间存在统计学差异。两组中间接测热法和人体测量法之间均存在显著相关性。仅在对照组中，我们发现间接测热法与人体测量法之间以及间接测热法与生物电阻抗分析法之间存在显著相关性。我们可以得出结论：（1）与健康对照者相比，肝硬化患者的静息能量消耗没有变化；（2）生物电阻抗是一种计算身体成分并由此得出能量消耗的有用方法；然而，它仅在健康人群中能给出合适的结果，在肝硬化患者中只能得出近似值。
