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单髁骨关节异体骨在膝关节周围重建中的应用。

The use of unicondylar osteoarticular allografts in reconstructions around the knee.

作者信息

Bianchi Giuseppe, Staals Eric L, Donati Davide, Mercuri Mario

机构信息

Istituti Ortopedici Rizzoli, 5th Division, Via Pupilli, 1-40136 Bologna, Italy.

出版信息

Knee. 2009 Jan;16(1):1-5. doi: 10.1016/j.knee.2008.07.011. Epub 2008 Oct 26.

DOI:10.1016/j.knee.2008.07.011
PMID:18954989
Abstract

Unicondylar osteoarticular allografts (UOA) of the knee are mainly used after bone tumour resections for benign aggressive tumours or small malignant tumours with clearly defined margins. They are also used less often in large posttraumatic condylar defects. Between 1989 and 2004, 12 deep-frozen UOA reconstructions (in 11 patients) were performed at our Institute. The diagnosis was chondrosarcoma in four cases, giant cell tumour in three, osteosarcoma in three, posttraumatic defect in one, and one failed UOA. The involved site was the medial femoral condyle in six cases, the lateral femoral condyle in three, the medial side of the tibial plateau in two, and the lateral in one case. One allograft was removed after 29 months because of an intra-articular displaced fracture, and substituted with a new UOA. One patient died of metastatic disease at 24 months. We report the functional and radiographical outcome of the remaining 10 UOAs with a minimum follow-up of 4 years (average 11 years). Two of the 10 patients had excellent results, five were good and three were fair. Radiographically, five patients had "mild" and five had "severe" degenerative changes. One patient with severe degenerative changes had pain and stiffness, therefore the UOA was converted into a prosthesis allograft composite, using a conventional total knee prosthesis. In selected cases of distal femoral and proximal tibial tumours, UOA reconstructions give good functional outcomes with relatively few major complications.

摘要

膝关节单髁骨关节异体移植术(UOA)主要用于良性侵袭性肿瘤或边界清晰的小恶性肿瘤切除术后的骨肿瘤患者。它也较少用于大型创伤后髁部缺损。1989年至2004年期间,我院共进行了12例(11名患者)深冻UOA重建手术。诊断结果为软骨肉瘤4例,骨巨细胞瘤3例,骨肉瘤3例,创伤后缺损1例,1例UOA移植失败。受累部位为内侧股骨髁6例,外侧股骨髁3例,胫骨平台内侧2例,外侧1例。1例同种异体移植因关节内移位骨折在29个月后取出,并用新的UOA替代。1例患者在24个月时死于转移性疾病。我们报告了其余10例UOA的功能和影像学结果,随访时间最短为4年(平均11年)。10例患者中2例结果优秀,5例良好,3例一般。影像学检查显示,5例患者有“轻度”退变,5例有“重度”退变。1例重度退变患者出现疼痛和僵硬,因此使用传统全膝关节假体将UOA转换为假体异体复合移植。在股骨远端和胫骨近端肿瘤的特定病例中,UOA重建可获得良好的功能结果,且主要并发症相对较少。

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