Xiao Ting, Xia Li-Xin, Yang Zhen-Hai, He Chun-Di, Gao Xing-Hua, Chen Hong-Duo
Department of Dermatology, No. 1 Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China.
Eur J Dermatol. 2008 Nov-Dec;18(6):660-2. doi: 10.1684/ejd.2008.0515. Epub 2008 Oct 27.
Recently there have been some reports concerned the treatment of early stage mycosis fungoides (MF) with narrow-band ultraviolet B (NB-UVB) phototherapy. In most of the previous reports, NB-UVB phototherapy was given three times a week on non-consecutive days. Our aim was to evaluate the effect of a twice weekly regimen of NB-UVB phototherapy in the treatment of early-stage MF. Eight patients with early stage MF received NB-UVB phototherapy twice weekly. Six patients (75%) had a complete response in a mean of 23.4 treatments, two (25%) had a partial response. Upon discontinuation of treatment, four patients with complete response relapsed in a mean time to relapse of 5 months. The twice weekly regimen of NB-UVB phototherapy is effective and well-tolerated in the treatment of early stage MF.
最近有一些关于窄谱中波紫外线（NB-UVB）光疗治疗早期蕈样肉芽肿（MF）的报道。在之前的大多数报道中，NB-UVB光疗每周进行三次，且非连续进行。我们的目的是评估NB-UVB光疗每周两次方案治疗早期MF的效果。8例早期MF患者接受了每周两次的NB-UVB光疗。6例患者（75%）在平均23.4次治疗后完全缓解，2例（25%）部分缓解。停止治疗后，4例完全缓解的患者复发，平均复发时间为5个月。NB-UVB光疗每周两次方案治疗早期MF有效且耐受性良好。
