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Prandial insulin and the systemic appearance of meal-derived glucose in people with type 1 diabetes.

作者信息

Vella Adrian, Shah Pankaj, Basu Ananda, Rizza Robert A

出版信息

Diabetes Care. 2008 Nov;31(11):2230-1. doi: 10.2337/dc08-1549.

DOI:10.2337/dc08-1549
PMID:18955720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2571049/
Abstract
摘要

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Prandial insulin and the systemic appearance of meal-derived glucose in people with type 1 diabetes.1型糖尿病患者的餐时胰岛素与膳食来源葡萄糖的全身表现
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Insulin administration and rate of glucose appearance in people with type 1 diabetes.1型糖尿病患者的胰岛素给药与葡萄糖出现率
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Many patients with Type 1 diabetes estimate their prandial insulin need inappropriately.许多 1 型糖尿病患者对他们的餐时胰岛素需求量估计不准确。
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The dual-wave bolus feature in continuous subcutaneous insulin infusion pumps controls prolonged post-prandial hyperglycaemia better than standard bolus in Type 1 diabetes.在1型糖尿病中，持续皮下胰岛素输注泵的双波大剂量给药功能比标准大剂量给药能更好地控制餐后高血糖的持续时间。
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本文引用的文献

1
Insulin administration and rate of glucose appearance in people with type 1 diabetes.1型糖尿病患者的胰岛素给药与葡萄糖出现率
Diabetes Care. 2008 Nov;31(11):2183-7. doi: 10.2337/dc08-0705. Epub 2008 Jul 23.
2
Effects of dipeptidyl peptidase-4 inhibition on gastrointestinal function, meal appearance, and glucose metabolism in type 2 diabetes.二肽基肽酶-4抑制对2型糖尿病患者胃肠功能、进餐情况及糖代谢的影响
Diabetes. 2007 May;56(5):1475-80. doi: 10.2337/db07-0136. Epub 2007 Feb 15.
3
Assessment of postprandial glucose metabolism: conventional dual- vs. triple-tracer method.餐后葡萄糖代谢评估：传统双示踪剂法与三示踪剂法对比
Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E800-6. doi: 10.1152/ajpendo.00461.2005. Epub 2006 May 23.
4
The gastrointestinal tract and glucose tolerance.
Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):479-84. doi: 10.1097/01.mco.0000134375.01310.97.
5
Use of a novel triple-tracer approach to assess postprandial glucose metabolism.使用一种新型三重示踪剂方法评估餐后葡萄糖代谢。
Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E55-69. doi: 10.1152/ajpendo.00190.2001.
6
Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration.1型糖尿病在肠内给予葡萄糖期间不会改变最初的内脏葡萄糖摄取或肝脏尿苷二磷酸葡萄糖通量。
Diabetologia. 2001 Jun;44(6):729-37. doi: 10.1007/s001250051682.
7
Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus.在2型糖尿病患者中，胰高血糖素抑制作用的缺乏会导致餐后高血糖。
J Clin Endocrinol Metab. 2000 Nov;85(11):4053-9. doi: 10.1210/jcem.85.11.6993.
8
Simultaneous time-varying systemic appearance of oral and hepatic glucose in adults monitored with stable isotopes.用稳定同位素监测成年人口腔和肝脏葡萄糖的同时时变全身出现情况。
Am J Physiol. 1998 Oct;275(4):E717-28. doi: 10.1152/ajpendo.1998.275.4.E717.
9
Effects of a change in the pattern of insulin delivery on carbohydrate tolerance in diabetic and nondiabetic humans in the presence of differing degrees of insulin resistance.在存在不同程度胰岛素抵抗的情况下，胰岛素给药模式的改变对糖尿病和非糖尿病患者碳水化合物耐量的影响。
J Clin Invest. 1996 May 15;97(10):2351-61. doi: 10.1172/JCI118678.
10
13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus.正常受试者和胰岛素依赖型糖尿病患者肝脏葡萄糖代谢的13C核磁共振波谱研究
J Clin Invest. 1994 Dec;94(6):2369-76. doi: 10.1172/JCI117602.