Dunais Brigitte, Bruno Pascale, Carsenti-Dellamonica Hélène, Touboul Pia, Dellamonica Pierre, Pradier Christian
Service d'Infectiologie and daggerDépartement de Santé Publique, CHU de Nice, France.
Pediatr Infect Dis J. 2008 Nov;27(11):1033-5. doi: 10.1097/INF.0b013e31817bb8cf.
Pneumococcal nasopharyngeal carriage, serotype distribution, and penicillin-susceptibility were monitored among children attending daycare centers in France from 1999 to 2006 to assess the impact of pneumococcal conjugate vaccine and antibiotic-reducing policies. Pneumococcal carriage remained stable. Immunization rates reached 68% in 2006. Serotype distribution shifted significantly from vaccine serotypes to vaccine-related and nonvaccine serotypes. Antibiotic treatments fell by 50%.
1999年至2006年期间，对法国日托中心的儿童进行了肺炎球菌鼻咽携带情况、血清型分布及青霉素敏感性监测，以评估肺炎球菌结合疫苗和减少抗生素使用政策的影响。肺炎球菌携带情况保持稳定。2006年免疫接种率达到68%。血清型分布从疫苗血清型显著转向疫苗相关血清型和非疫苗血清型。抗生素治疗减少了50%。
