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[刚果布拉柴维尔南部地区保健中心的疟疾情况]

[Malaria in health centres in the southern districts of Brazzaville, Congo].

作者信息

Ndounga M, Casimiro P N, Miakassissa-Mpassi V, Loumouamou D, Ntoumi F, Basco L K

机构信息

Centre d'études sur les ressources végétales, BP 1249, Brazzaville, Congo.

出版信息

Bull Soc Pathol Exot. 2008 Oct;101(4):329-35. doi: 10.3185/pathexo3111.

Abstract

During the surveys on antimalarial drug efficacy carried out from 2003 to 2006, we systematically checked the presence of Plasmodium falciparum in patients consulting in two health centres located in the south of Brazzaville. The first centre is situated in the urban zone; the second, in the semi rural area. The objective of this survey was to determine the prevalence of malaria-infected patients among the consulting patients and the prevalence of symptomatic patients with acute malaria attacks based on the parasitic density. Patients with parasites were assigned to one of the 5 following classifications: <2000, > or =2000, <5000, > or =5000 and > or =10,000 asexual parasites/microl of blood. Based on the threshold of parasite density 10,000 asexual parasites/microl, 10% and 24% of febrile patients in Tenrikyo and Madibou health centres were diagnosed as cases of malaria, respectively; 13.6% and 26.8% of patients under 5 years old consulting in these two health centres had malaria attacks. If the threshold of parasite density is lowered to 2000 asexual parasites/microl for patients > or =15 years old, 8% and 14% of adults in Tenrikyo and Madibou had malaria attacks, respectively The malaria burden was higher in the periphery of the city of Brazzaville than in the urbanized central districts. The Madibou health centre located in semi rural zone receives twice as many malaria cases for consultation than Tenrikyo located in the urban zone.

摘要

在2003年至2006年进行的抗疟药物疗效调查中,我们系统地检查了位于布拉柴维尔南部的两个保健中心就诊患者中恶性疟原虫的存在情况。第一个中心位于市区;第二个位于半农村地区。这项调查的目的是根据寄生虫密度确定就诊患者中疟疾感染患者的患病率以及急性疟疾发作的有症状患者的患病率。寄生虫检测呈阳性的患者被分为以下5种分类之一:<2000、≥2000、<5000、≥5000和≥10,000个无性寄生虫/微升血液。以寄生虫密度阈值10,000个无性寄生虫/微升计算,天理教和马迪布保健中心分别有10%和24%的发热患者被诊断为疟疾病例;在这两个保健中心就诊的5岁以下患者中,分别有13.6%和26.8%发生疟疾发作。如果将≥15岁患者的寄生虫密度阈值降低到2000个无性寄生虫/微升,天理教和马迪布分别有8%和14%的成年人发生疟疾发作。布拉柴维尔市周边地区的疟疾负担高于城市化的中心地区。位于半农村地区的马迪布保健中心接收的疟疾咨询病例数量是位于市区的天理教的两倍。

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