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刚果共和国的疟疾流行病学研究。

Malaria epidemiological research in the Republic of Congo.

作者信息

Koukouikila-Koussounda Felix, Ntoumi Francine

机构信息

Fondation Congolaise Pour la Recherche Médicale, Villa D6, WHO AFRO Campus, Brazzaville, Republic of Congo.

Faculty of Sciences and Techniques, University Marien Ngouabi, Brazzaville, Republic of Congo.

出版信息

Malar J. 2016 Dec 23;15(1):598. doi: 10.1186/s12936-016-1617-7.

Abstract

BACKGROUND

Reliable and comprehensive information on the burden of malaria is critical for guiding national and international efforts in malaria control. The purpose of this review is to provide an overview of published data and available information on malaria resulting from field studies/investigations conducted in the Republic of Congo (RoC) from 1992 to 2015, as baseline for assisting public health authorities and researchers to define future research priorities as well as interventions.

METHODS

This review considers data from peer-reviewed articles and information from the National Malaria Control Programme reports, based on field investigations or samples collected from 1992 to 2015. Peer-reviewed papers were searched throughout online bibliographic databases PubMed, HINARI and Google Scholar using the following terms: "malaria", "Congo", "Brazzaville", "prevalence", "antimalarial", "efficacy", "falciparum", "genetic", "diversity". Original articles and reviews were included and selection of relevant papers was made.

RESULTS

Twenty-eight published articles were included in this review and two additional records from the National Malaria Control Programme were also considered. The majority of studies were conducted in Brazzaville and Pointe-Noire.

CONCLUSION

The present systematic review reveals that number of studies have been conducted in the RoC with regard to malaria. However, their results cannot formally be generalized at the country level. This suggests a need for implementing regular multisite investigations and surveys that may be representative of the country, calling for the support and lead of the Ministry of Health.

摘要

背景

关于疟疾负担的可靠且全面的信息对于指导国家和国际疟疾控制工作至关重要。本综述的目的是概述1992年至2015年在刚果共和国(RoC)进行的实地研究/调查所产生的已发表数据和有关疟疾的现有信息,作为协助公共卫生当局和研究人员确定未来研究重点及干预措施的基线。

方法

本综述考虑了同行评审文章中的数据以及国家疟疾控制计划报告中的信息,这些数据和信息基于1992年至2015年进行的实地调查或采集的样本。使用以下术语在在线书目数据库PubMed、HINARI和谷歌学术中搜索同行评审论文:“疟疾”、“刚果”、“布拉柴维尔”、“患病率”、“抗疟药”、“疗效”、“恶性疟原虫”、“基因”、“多样性”。纳入了原创文章和综述,并进行了相关论文的筛选。

结果

本综述纳入了28篇已发表文章,还考虑了国家疟疾控制计划的另外两份记录。大多数研究在布拉柴维尔和黑角进行。

结论

本次系统综述表明,在刚果共和国已开展了一些关于疟疾的研究。然而,其结果不能在国家层面正式推广。这表明需要开展可能代表该国情况的定期多地点调查和普查,这需要卫生部的支持和牵头。

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