Spadaro A, Iagnocco A, Baccano G, Ceccarelli F, Sabatini E, Valesini G
Dipartimento di Clinica e Terapia Medica, Divisione di Reumatologia Sapienza, Università di Roma, Azienda Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy.
Ann Rheum Dis. 2009 Oct;68(10):1559-63. doi: 10.1136/ard.2008.093351. Epub 2008 Oct 28.
An observational case-control study was designed to analyse the discriminative value of ultrasound (US)-detected joint effusion compared with physical examination in the assessment of sacroiliac joints (SIJ) in patients with spondyloarthropathy (SpA) with or without inflammatory back pain (IBP).
45 patients with SpA, classified according to European Spondylarthropathy Study Group criteria, and 30 healthy volunteers were studied. All patients had clinical evaluation of the SIJ, Bath ankylosing spondylitis (AS) metrology index, Bath AS disease activity index, Bath AS functional index, health assessment questionnaire, patient's and physician's visual analogue scale on global disease activity.
Ultrasound showed joint effusion in 38.9% of SIJ of patients with SpA and in 1.7% of SIJ of controls (p<0.001). The presence of IBP was significantly associated with SIJ effusion assessed by US alone or plus at least one SIJ test. SIJ effusion assessed by US alone or plus at least one SIJ test had a positive likelihood ratio (LR) (2.67 and 4.04, respectively) for the presence of IBP higher than LR of single clinical tests. Positive sacral sulcus test, iliac gapping and midline sacral thrust test were associated with SIJ effusion assessed by US, but all clinical tests, singly and in various combinations, had a low LR for the presence of SIJ effusion assessed by US.
The study suggests that high resolution sonography is useful in the assessment of SIJ involvement in SpA, resulting in images that are fast and inexpensive and may locate, complementing the physical examination, the origin of IBP.
设计一项观察性病例对照研究,分析在评估伴或不伴炎性背痛(IBP)的脊柱关节病(SpA)患者骶髂关节(SIJ)时,超声(US)检测到的关节积液与体格检查相比的鉴别价值。
对45例根据欧洲脊柱关节病研究组标准分类的SpA患者和30名健康志愿者进行研究。所有患者均对SIJ进行了临床评估、巴斯强直性脊柱炎(AS)计量指数、巴斯AS疾病活动指数、巴斯AS功能指数、健康评估问卷、患者和医生关于整体疾病活动的视觉模拟量表。
超声显示SpA患者中38.9%的SIJ存在关节积液,而对照组中这一比例为1.7%(p<0.001)。IBP的存在与单独通过超声或加上至少一项SIJ检查评估的SIJ积液显著相关。单独通过超声或加上至少一项SIJ检查评估的SIJ积液对于IBP存在的阳性似然比(LR)(分别为2.67和4.04)高于单项临床检查的LR。阳性骶沟试验、髂骨分离试验和中线骶骨推力试验与通过超声评估的SIJ积液相关,但所有临床检查单独或各种组合对于通过超声评估的SIJ积液存在的LR均较低。
该研究表明,高分辨率超声在评估SpA患者的SIJ受累情况时有用,能快速且低成本地生成图像,可定位IBP的起源,补充体格检查。