Nenezić Dragoslav, Matić Predrag, Gajin Predrag, Iijevski Nenad, Jocić Dario, Popov Petar, Milicić Miroslav, Radak Djordje
Srp Arh Celok Lek. 2008 Jul-Aug;136(7-8):410-3. doi: 10.2298/sarh0808410n.
Although the incidence is low, infection of prosthetic vascular graft bears a high incidence of serious complications including 25-75% mortality rate and 40-75% limb loss. The standard treatment of vascular graft infection consists of excision of the prosthesis, wound debridement and extraanatomic revascularization. Conservative treatment might be an option in a limited number of patients. We present three cases of surgical and conservative treatment of vascular graft infection.
Case 1: A patient developed silver-coated graft infection after femorodistal arterial reconstruction performed because of critical limb ischemia. In the early postoperative period, massive skin and subcutaneous tissue necrosis developed, with the graft being exposed. After two months of persistent debridement and wound toilette, the defect was covered with aThiersch skin graft. Case 2: PTFE graft infection in the right groin followed reconstruction of the isolated common femoral artery aneurysm. This graft was replaced with a silver-coated graft in situ. Reinfection of the proximal end of the implanted silver-coated graft occurred and the graft was exposed. After repeated debridement and wound toilette, the exposed prosthesis was covered with granulomatous tissue, and the wound healed. Case 3: A year after anastomotic pseudoaneurysm resection in the left groin, prosthesis was exposed following wound infection. This graft was substituted with a silver-coated graft in situ. The wound healed primarily.
These three cases demonstrate that under some circumstances vascular prosthesis infection can be successfully treated conservatively without graft removal, and also by in situ replacement using silver-coated graft.
尽管人工血管感染的发生率较低,但严重并发症的发生率却很高,包括25%-75%的死亡率和40%-75%的肢体缺失率。人工血管感染的标准治疗方法包括切除假体、伤口清创和解剖外血管重建。在少数患者中,保守治疗可能是一种选择。我们介绍三例人工血管感染的手术和保守治疗病例。
病例1:一名患者因严重肢体缺血接受股腘动脉重建术后发生银涂层移植物感染。术后早期,出现大量皮肤和皮下组织坏死,移植物外露。经过两个月的持续清创和伤口冲洗,缺损处用蒂尔施皮片覆盖。病例2:孤立性股总动脉瘤重建术后右腹股沟发生聚四氟乙烯移植物感染。该移植物原位更换为银涂层移植物。植入的银涂层移植物近端再次感染,移植物外露。经过反复清创和伤口冲洗,外露的假体被肉芽肿组织覆盖,伤口愈合。病例3:左腹股沟吻合口假性动脉瘤切除术后一年,伤口感染后假体外露。该移植物原位更换为银涂层移植物。伤口一期愈合。
这三例病例表明,在某些情况下,人工血管感染可以通过不切除移植物的保守治疗成功治愈,也可以通过使用银涂层移植物原位更换来治愈。