Qin Yang, Xu Youxuan, Yang Shumin, Zhu Shaotang
China Anti-Doping Agency, Beijing 100029, China.
Se Pu. 2008 Jul;26(4):431-6.
High performance liquid chromatography-mass spectrometry (LC-MS) has enabled the determination of most of the prohibited drugs in doping analysis, including many small molecular doping agents and peptide hormones. This paper reviews liquid chromatography-mass spectrometry for the screening, identification and quantification of doping agents in urine and other biological samples. Criteria for the identification of compounds by LC-MS are also discussed.
高效液相色谱-质谱联用技术（LC-MS）已能够测定兴奋剂检测中的大多数违禁药物，包括许多小分子兴奋剂和肽类激素。本文综述了液相色谱-质谱联用技术在尿液及其他生物样品中兴奋剂筛查、鉴定和定量分析方面的应用。还讨论了通过LC-MS鉴定化合物的标准。
