Yim K K, Lineaweaver W C, Siko P P, Buncke H J
Microsurgical Replantation Transplantation Department Davies Medical Center, San Francisco, CA 94114.
Microsurgery. 1991;12(4):262-7. doi: 10.1002/micr.1920120407.
A microvascular free muscle flap in rats using the anterior and posterior gracilis muscles with femoral vessels as its pedicle is presented. The gracilis muscles form a single unit supplied by the muscular branch artery and vein, averaging 0.3 mm and 0.4 mm in diameter, respectively. These small sizes preclude their use in transplantation. However, the muscular branch vessels in continuity with the femoral vessels can be used for the vascular pedicle in this muscle transplant. This muscle flap was transplanted to the contralateral femoral vessels by end-to-end anastomosis in 15 rats. Thirteen animals survived and 11 flaps were viable at 3 days for a success rate of 85%. The gracilis flaps averaged 674 mg in weight, 1.87 cm X 1.36 cm in size, and 7.23 mm in pedicle length. This free muscle flap model is reliable, relatively easy to perform, and provides adequate muscle bulk for pharmacologic and biochemical studies in transplanted muscle. No lower extremity complications were noted following femoral vessel ligations.
介绍了一种以股血管为蒂的大鼠股薄肌微血管游离肌皮瓣。股薄肌由肌肉分支动脉和静脉供血，形成一个单一单元，其直径平均分别为0.3毫米和0.4毫米。这些小尺寸使其无法用于移植。然而，与股血管相连的肌肉分支血管可用于该肌肉移植的血管蒂。将此肌皮瓣通过端端吻合移植到15只大鼠的对侧股血管。13只动物存活，11个肌皮瓣在3天时存活，成功率为85%。股薄肌皮瓣平均重量为674毫克，大小为1.87厘米×1.36厘米，蒂长为7.23毫米。这种游离肌皮瓣模型可靠，操作相对容易，为移植肌肉的药理和生化研究提供了足够的肌肉量。股血管结扎后未发现下肢并发症。
