Panattoni E, Marcucci M, Gabriele M, Natale M L, Blandizzi C, Bernardini N, Del Tacca M
Istituto di Clinica Odontoiatrica, Università degli Studi di Pisa.
Minerva Stomatol. 1991 Apr;40(4):273-6.
The clinical efficacy of a macrolide antibiotic, roxithromycin, was evaluated in 24 patients affected by acute odontogenic infections. Patients were treated with a first dose of 300 mg p.o. which was followed by 150 mg p.o. 12-hourly for the following two days. Total responses were evaluated by an arbitrary scale. The results showed that an excellent and good response was obtained in 99.96% of treated patients. On the basis of clinically compared data and the drug safety it may be concluded that roxithromycin can be successfully used in the treatment of odontogenic infections.
对24例急性牙源性感染患者评估了一种大环内酯类抗生素罗红霉素的临床疗效。患者口服首剂300mg,随后两天每日两次、每次150mg口服给药。采用一种任意标准评估总体反应。结果显示,99.96%的治疗患者获得了优和良的反应。基于临床比较数据和药物安全性,可得出结论,罗红霉素可成功用于治疗牙源性感染。