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圣地亚哥海军训练中心甲型病毒性肝炎暴发:流行病学评估

An outbreak of type A viral hepatitis at the Naval Training Center, San Diego: epidemiologic evaluation.

作者信息

Hooper R R, Juels C W, Routenberg J A, Harrison W O, Kilpatrick M E, Kendra S J, Dienstag J L

出版信息

Am J Epidemiol. 1977 Feb;105(2):148-55. doi: 10.1093/oxfordjournals.aje.a112367.

Abstract

In October 1974, a large foodborne outbreak of hepatitis occurred among naval personnel undergoing basic training at the Naval Training Center, San Diego, California. Of the 2781 recruits eating at the implicated dining hall on the day disease transmission occurred, 133 developed clinical or laboratory evidence of hepatitis for an attack rate of 47.8/1000. The epidemiologic investigation suggested that hepatitis A virus was the etiologic agent, and this was subsequently confirmed by laboratory examination. The index and source case was a recuit food-handler who experienced prodromal symptoms of hepatitis while preparing salads and fresh fruit 32 days prior to the outbreak. A food preference questionnaire implicated tossed salad and fresh grapefruit as the specific vehicles of transmission.

摘要

1974年10月,在加利福尼亚州圣地亚哥海军训练中心接受基础训练的海军人员中发生了一起大规模食源性肝炎暴发。在疾病传播当天在受牵连食堂就餐的2781名新兵中,133人出现了肝炎的临床或实验室证据,发病率为47.8/1000。流行病学调查表明甲型肝炎病毒是病原体,随后通过实验室检查得到证实。首例及传染源是一名新兵食品处理人员,在疫情暴发前32天准备沙拉和新鲜水果时出现了肝炎前驱症状。一份食物偏好问卷表明凉拌沙拉和新鲜葡萄柚是具体的传播媒介。

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