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[急性婴幼儿腹泻时口服补液盐(ORS 90)与“超溶液”的比较]

[Comparison of an oral rehydration solution (ORS 90) and a "supersolution" during acute infantile diarrhea].

作者信息

Melaranci C, Giammaria P, Dardano B

机构信息

IIa Divisione, Ospedale Bambino Gesu, Roma, Italia.

出版信息

Pediatr Med Chir. 1991 Mar-Apr;13(2):165-7.

PMID:1896383
Abstract

As acute diarrhoea gives rise to a loss of water and electrolytes, the most effective therapy results the oral rehydration. Harrison and Darrow tried this way first. Only in the years '60 we began to use oral rehydration commonly. Usually, solutions contain glucose, Na, K, Cl, Bicarbonate in various concentration. When glucose is replaced by rice starch or when amino acid are added, then we have a "supersolution". Nutrients intake provides more calories and increases absorption Na-depending. We used one of these new "supersolutions". Two groups of children, hospitalised for acute diarrhoea, were treated with different rehydration solutions. The first one (Dicodral Forte), prepared according to the WHO, contains glucose and electrolytes as we know. The second one (Amidral) has rice starch instead of glucose and presents a lower concentration of Na and Cl. The present study looked over: A) Weight increase from the first to the third day of hospitalisation in our department. B) Duration of diarrhea. C) Number of stools. D) Haematological values before and after rehydration. All the patients ingested the same amount of solution. Children which received WHO's solution presented diarrhea longer than others (2.55 +/- 2.06 vs 2.2 +/- 1.1 days). Number of stools was below average too (3.05 +/- 2.64 vs 2.8 +/- 1.5). Refeeding was done employing the same milk used in former times. AMIDRAL was used to dilute the milk when it was possible. Most important result is the increase of weight we had using this "supersolution". 15/20 children which received AMIDRAL showed an increase of their weight as shown in Tab. 1.

摘要

由于急性腹泻会导致水分和电解质流失,最有效的治疗方法是口服补液。哈里森和达罗首先尝试了这种方法。直到60年代,我们才开始普遍使用口服补液。通常,溶液含有不同浓度的葡萄糖、钠、钾、氯、碳酸氢盐。当葡萄糖被大米淀粉替代或添加氨基酸时,我们就得到了一种“超级溶液”。营养物质的摄入提供了更多热量,并增加了钠依赖性吸收。我们使用了其中一种新的“超级溶液”。两组因急性腹泻住院的儿童接受了不同的补液溶液治疗。第一组(强力迪可多)是按照世界卫生组织的配方配制的,含有我们所熟知的葡萄糖和电解质。第二组(阿米达尔)用大米淀粉替代了葡萄糖,且钠和氯的浓度较低。本研究观察了:A)在我们科室住院第一天到第三天的体重增加情况。B)腹泻持续时间。C)排便次数。D)补液前后的血液学指标。所有患者摄入的溶液量相同。接受世界卫生组织配方溶液治疗的儿童腹泻时间比其他儿童长(2.55±2.06天对2.2±1.1天)。排便次数也低于平均水平(3.05±2.64次对2.8±1.5次)。重新喂食时使用的是以前用的同一种牛奶。如有可能,用阿米达尔稀释牛奶。最重要的结果是使用这种“超级溶液”后体重增加。接受阿米达尔治疗的20名儿童中有15名体重增加,如表1所示。

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