Chen D, Ríos A, Castro M D, Valcárcel M
Department of Analytical Chemistry, Faculty of Sciences, University of Córdoba, 14004 Córdoba, Spain.
Talanta. 1991 Nov;38(11):1227-33. doi: 10.1016/0039-9140(91)80097-j.
Chlorpromazine and promethazine were simultaneously determined by irradiating flow-injection manifolds with ultraviolet light. The simultaneous determination was based on the difference in pH of the media where the photochemical conversion of each phenothiazine into a fluorescent product took place. The choice of the best flow-injection configuration and mathematical treatment for solving the mixtures are discussed. Chlorpromazine and promethazine can be simultaneously determined at the mug/ml level with r.s.d. values between 2 and 4% and sampling frequencies in the range 30-40/hr.
通过用紫外光照射流动注射流路同时测定氯丙嗪和异丙嗪。该同时测定基于每种吩噻嗪光化学转化为荧光产物所处介质的pH差异。讨论了最佳流动注射配置的选择以及用于解决混合物问题的数学处理方法。氯丙嗪和异丙嗪可在微克/毫升水平同时测定，相对标准偏差值在2%至4%之间，采样频率在30 - 40次/小时范围内。
