Pacella C M, Papini E, Valle D, Buffa E, Bizzarri G, Rossi Z, Nardi F
Servizio di Radiologia, Ospedale Regina Apostolorum, Albano Laziale (RM).
Radiol Med. 1991 Jul-Aug;82(1-2):89-94.
CT-guided fine-needle aspiration biopsy (FNAB) was performed on the patients with pulmonary or mediastinal masses to obtain material for cytologic/histologic diagnosis. Diagnostic accuracy and safety of the technique were evaluated in 75 patients affected with thoracic lesions still undiagnosed after thorough radiological and endoscopic investigations. The cytologic and/or microhistologic samples allowed a correct diagnosis to be made in 61 cases (81%), with no false positives and 7 false negatives (9%). The samples were inadequate for diagnostic purposes in 7 cases (9%). Specificity, sensitivity, and diagnostic accuracy were 68%, 76%, and 81%, respectively. No major complication was recorded and a case of asymptomatic pneumothorax resolved spontaneously within 48 hours. CT-guided FNAB of space-occupying lesions in the lung and mediastinum is therefore a rapid and valuable diagnostic tool and is quite safe when performed by skilled operators.
对患有肺部或纵隔肿块的患者进行CT引导下细针穿刺活检（FNAB），以获取用于细胞学/组织学诊断的材料。在75例经全面影像学和内镜检查后仍未确诊的胸部病变患者中，评估了该技术的诊断准确性和安全性。细胞学和/或微组织学样本在61例（81%）病例中做出了正确诊断，无假阳性，7例假阴性（9%）。7例（9%）样本因诊断目的不足。特异性、敏感性和诊断准确性分别为68%、76%和81%。未记录到重大并发症，1例无症状气胸在48小时内自发缓解。因此，CT引导下对肺和纵隔占位性病变进行FNAB是一种快速且有价值的诊断工具，由熟练操作人员进行时相当安全。
