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基于蛋白质:肌酐比值从单次尿液样本中测定定量蛋白尿

[Determination of quantitative proteinuria from a single urine sample based on the protein:creatinine ratio].

作者信息

Jarosová A, Temlík V, Monhart V

机构信息

Ustrední vojenská nemocnice, Praha.

出版信息

Vnitr Lek. 1991 Jun;37(6):535-40.

PMID:1897137
Abstract

Assessment of quantitative proteinuria is associated with collection of urine over several hours. This is, however, not always possible, in particular in ambulatory patients. Therefore efforts are made to assess the urinary protein per 24 hours on the basis of the proteinuria index, i.e. the ratio protein:creatinine in a single urine specimen. In a group of forty patients the authors demonstrated the closest correlation (correlation coefficient = 0.910374) between quantitative proteinuria and the index of proteinuria in urine specimens which were collected during daily activity. The closeness of this correlation depends on renal function. Assessment of quantitative proteinuria from a single urine sample on the basis of the protein:creatinine ratio is therefore useful in subjects with a preserved or not very restricted renal function.

摘要

定量蛋白尿的评估与数小时的尿液收集有关。然而,这并非总是可行的,尤其是对于门诊患者。因此,人们努力根据蛋白尿指数,即单次尿液标本中蛋白质与肌酐的比值,来评估每24小时的尿蛋白量。作者在一组40名患者中证明,在日常活动期间收集的尿液标本中,定量蛋白尿与蛋白尿指数之间存在最密切的相关性(相关系数 = 0.910374)。这种相关性的密切程度取决于肾功能。因此,基于蛋白质与肌酐比值从单次尿液样本评估定量蛋白尿,对于肾功能正常或受限程度不严重的受试者是有用的。

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