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1
Similar outcomes among black and white renal allograft recipients.黑人与白人肾移植受者的相似结局。
J Am Soc Nephrol. 2009 Jan;20(1):172-9. doi: 10.1681/ASN.2007070820. Epub 2008 Oct 29.
2
Black Ethnicity is Not a Risk Factor for Mortality or Graft Loss After Kidney Transplant in the United Kingdom.在英国,黑人种族并非肾移植后死亡或移植物丢失的风险因素。
Exp Clin Transplant. 2018 Dec;16(6):682-689. doi: 10.6002/ect.2018.0241. Epub 2018 Oct 5.
3
Patient and Kidney Allograft Survival with National Kidney Paired Donation.全国肾脏配对捐赠计划中患者和肾脏移植物的存活率。
Clin J Am Soc Nephrol. 2020 Feb 7;15(2):228-237. doi: 10.2215/CJN.06660619. Epub 2020 Jan 28.
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Preemptive deceased donor kidney transplantation: considerations of equity and utility.抢先进行已故供者肾移植:公平性和实用性的考虑。
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Donor ethnicity influences outcomes following deceased-donor kidney transplantation in black recipients.供体种族会影响黑人受者接受死亡供体肾移植后的结果。
J Am Soc Nephrol. 2008 Oct;19(10):2011-9. doi: 10.1681/ASN.2008010078. Epub 2008 Jul 23.
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Patient and allograft survival of Indo Asian and East Asian dialysis patients treated in Canada.在加拿大接受治疗的印度裔亚洲和东亚透析患者的患者及同种异体移植物存活率。
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Renal allograft survival in patients with oxalosis.草酸盐沉着症患者的同种异体肾移植存活率
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Do outcomes after kidney transplantation differ for black patients in England versus New York State? A comparative, population-cohort analysis.在英国与纽约州,黑人患者肾移植后的结果是否存在差异?一项比较性人群队列分析。
BMJ Open. 2017 May 9;7(5):e014069. doi: 10.1136/bmjopen-2016-014069.
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Overall Graft Loss Versus Death-Censored Graft Loss: Unmasking the Magnitude of Racial Disparities in Outcomes Among US Kidney Transplant Recipients.总体移植失败与死亡截尾移植失败:揭示美国肾移植受者结局中种族差异的程度。
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Practice patterns in arteriovenous fistula ligation among kidney transplant recipients in the United States Renal Data Systems.美国肾脏数据系统中肾移植受者动静脉瘘结扎的实践模式。
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Life on the Line: Prioritizing Equity in Kidney Transplantation for Populations Marginalized by Race and Ethnicity.生死攸关:为因种族和族裔而被边缘化的人群在肾脏移植中优先实现公平。
Can J Kidney Health Dis. 2025 Apr 10;12:20543581251331076. doi: 10.1177/20543581251331076. eCollection 2025.
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Immunologic Benefits of 0-antigen Mismatched Transplants: No Added Boost for Racial and Ethnic Minorities.O抗原不匹配移植的免疫益处:对少数族裔无额外促进作用
Transplant Direct. 2024 Jun 13;10(7):e1653. doi: 10.1097/TXD.0000000000001653. eCollection 2024 Jul.
3
Racialized and Immigrant Status and the Pursuit of Living Donor Kidney Transplant - a Canadian Cohort Study.种族化与移民身份以及活体肾移植的寻求——一项加拿大队列研究
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Exploring barriers to living donor kidney transplant for African, Caribbean and Black communities in the Greater Toronto Area, Ontario: a qualitative study protocol.安大略省大多伦多地区非裔、加勒比裔和黑人社区活体供肾移植障碍的探索:一项定性研究方案。
BMJ Open. 2023 Aug 16;13(8):e073176. doi: 10.1136/bmjopen-2023-073176.
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Donor characteristics and their impact on kidney transplantation outcomes: Results from two nationwide instrumental variable analyses based on outcomes of donor kidney pairs accepted for transplantation.供体特征及其对肾移植结果的影响:基于接受移植的供肾对结果的两项全国性工具变量分析结果
EClinicalMedicine. 2022 Jun 25;50:101516. doi: 10.1016/j.eclinm.2022.101516. eCollection 2022 Aug.
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Use and Outcomes of Induction Therapy in Well-Matched Kidney Transplant Recipients.匹配良好的肾移植受者中诱导治疗的应用和结果。
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Barriers to Accessing Kidney Transplantation Among Populations Marginalized by Race and Ethnicity in Canada: A Scoping Review Part 2-East Asian, South Asian, and African, Caribbean, and Black Canadians.加拿大因种族和族裔而被边缘化人群获得肾脏移植的障碍:范围综述 第2部分——东亚、南亚以及非洲、加勒比和加拿大黑人
Can J Kidney Health Dis. 2021 Mar 3;8:2054358121996834. doi: 10.1177/2054358121996834. eCollection 2021.
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Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes.新冠病毒住院患者中存在的种族差异并不会导致结果的差异。
Public Health. 2021 Jan;190:93-98. doi: 10.1016/j.puhe.2020.11.021. Epub 2020 Nov 28.
9
Referral for Kidney Transplantation in Canadian Provinces.加拿大各省的肾脏移植转诊。
J Am Soc Nephrol. 2019 Sep;30(9):1708-1721. doi: 10.1681/ASN.2019020127. Epub 2019 Aug 6.
10
Validation of Self-Reported Race in a Canadian Provincial Renal Administrative Database.加拿大省级肾脏管理数据库中自我报告种族的验证
Can J Kidney Health Dis. 2019 Jul 1;6:2054358119859528. doi: 10.1177/2054358119859528. eCollection 2019.

本文引用的文献

1
Income-related disparities in kidney transplant graft failures are eliminated by Medicare's immunosuppression coverage.医疗保险的免疫抑制药物覆盖范围消除了肾移植移植物失败方面与收入相关的差异。
Am J Transplant. 2008 Dec;8(12):2636-46. doi: 10.1111/j.1600-6143.2008.02422.x.
2
Mortality after kidney transplantation: a comparison between the United States and Canada.肾移植后的死亡率:美国与加拿大的比较。
Am J Transplant. 2006 Jan;6(1):109-14. doi: 10.1111/j.1600-6143.2005.01141.x.
3
Race/ethnicity, poverty status, and renal transplant outcomes.种族/民族、贫困状况与肾移植结果。
Transplantation. 2005 Oct 15;80(7):917-24. doi: 10.1097/01.tp.0000173379.53347.31.
4
Kidney transplant in black recipients: are African Europeans different from African Americans?黑人受者的肾移植:非洲裔欧洲人与非裔美国人有差异吗?
Am J Transplant. 2005 Nov;5(11):2682-7. doi: 10.1111/j.1600-6143.2005.01057.x.
5
Unraveling the racial disparities associated with kidney disease.揭示与肾脏疾病相关的种族差异。
Kidney Int. 2005 Sep;68(3):914-24. doi: 10.1111/j.1523-1755.2005.00485.x.
6
Kidney transplants in African Americans and non-African Americans: equivalent outcomes with living but not deceased donors.非裔美国人和非非裔美国人的肾移植:活体供体移植效果相当,但尸体供体移植效果不同。
Transplant Proc. 2005 Mar;37(2):699-700. doi: 10.1016/j.transproceed.2004.11.025.
7
Race and electronically measured adherence to immunosuppressive medications after deceased donor renal transplantation.死亡供体肾移植后种族与免疫抑制药物电子监测依从性
J Am Soc Nephrol. 2005 Jun;16(6):1839-48. doi: 10.1681/ASN.2004121059. Epub 2005 Mar 30.
8
Influence of race on kidney transplant outcomes within and outside the Department of Veterans Affairs.种族对退伍军人事务部内外肾移植结果的影响。
J Am Soc Nephrol. 2005 Jan;16(1):269-77. doi: 10.1681/ASN.2004040333. Epub 2004 Nov 24.
9
Access to renal transplantation for minority patients with ESRD in Canada.加拿大终末期肾病少数族裔患者接受肾移植的情况。
Am J Kidney Dis. 2004 Dec;44(6):1083-9. doi: 10.1053/j.ajkd.2004.08.031.
10
Death and renal transplantation among Aboriginal people undergoing dialysis.接受透析治疗的原住民中的死亡与肾移植情况。
CMAJ. 2004 Sep 14;171(6):577-82. doi: 10.1503/cmaj.1031859.

黑人与白人肾移植受者的相似结局。

Similar outcomes among black and white renal allograft recipients.

作者信息

Yeates Karen, Wiebe Natasha, Gill John, Sima Camelia, Schaubel Douglas, Holland David, Hemmelgarn Brenda, Tonelli Marcello

机构信息

Department of Medicine, Queen's University, 94 Stuart Street, Kingston, Ontario, Canada.

出版信息

J Am Soc Nephrol. 2009 Jan;20(1):172-9. doi: 10.1681/ASN.2007070820. Epub 2008 Oct 29.

DOI:10.1681/ASN.2007070820
PMID:18971374
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2615721/
Abstract

Black renal transplant recipients experience shorter graft survival than white recipients, but no published data describe the graft outcomes among black Canadian recipients. Here, we analyzed data from the Canadian national renal replacement therapy registry, which included 20,243 incident dialysis patients (3% black, 97% white), 5036 of whom received a renal transplant during the study period. Black patients were significantly less likely to receive a renal transplant (deceased and living-donor combined) when compared with white patients (hazard ratio 0.59; 95% confidence interval 0.51 to 0.69; P < 0.0001). Among patients who underwent a renal transplant, there was no significant difference in the likelihood of graft failure between black and white patients, even after adjustment for comorbidities and socioeconomic status; black patients, however, had significantly lower posttransplantation mortality compared with white patients (hazard ratio 0.49; 95% confidence interval 0.28 to 0.88; P = 0.02). In conclusion, graft outcomes between black and white Canadian renal transplant patients are similar. Because this differs from the experience reported from the United States, further direct comparisons between the two populations is warranted.

摘要

黑人肾移植受者的移植物存活时间比白人受者短,但尚无已发表的数据描述加拿大黑人受者的移植物结局。在此,我们分析了加拿大全国肾脏替代治疗登记处的数据,该数据包括20243例新发透析患者(3%为黑人,97%为白人),其中5036例在研究期间接受了肾移植。与白人患者相比,黑人患者接受肾移植(包括尸体供肾和活体供肾)的可能性显著降低(风险比0.59;95%置信区间0.51至0.69;P<0.0001)。在接受肾移植的患者中,即使在调整合并症和社会经济地位后,黑人和白人患者移植物失败的可能性也没有显著差异;然而,黑人患者移植后的死亡率显著低于白人患者(风险比0.49;95%置信区间0.28至0.88;P = 0.02)。总之,加拿大黑人和白人肾移植患者的移植物结局相似。由于这与美国报告的情况不同,因此有必要对这两个人群进行进一步的直接比较。