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[非增殖性糖尿病视网膜病变中的黄斑无血管区]

[The foveal avascular zone in nonproliferative diabetic retinopathy].

作者信息

Ivanisević M

机构信息

Klinicki bolnicki centar FIRULE, Split.

出版信息

Vojnosanit Pregl. 1991 Mar-Apr;48(2):128-30.

PMID:1897172
Abstract

The areas of the foveolar avascular zone (FAZ) were measured in the fluorescein angiograms and the comparison was made between 44 eyes of 22 diabetics with nonproliferative diabetic retinopathy and 32 eyes of the healthy nondiabetic controls. It was found that the area of the FAZ in diabetics ranged between a mean of 0.26 +/- 0.07 mm2 and in healthy nondiabetic controls 0.23 +/- 0.04 mm2 and it was statistically significant difference (p less than 0.05). The results obtained have shown that the area of the FAZ in diabetics with nonproliferative retinopathy is significantly larger than in healthy eyes due to the destruction of the parafoveal capillary net, although the area of the FAZ in healthy eyes could considerably vary. The importance of fluorescein angiography in measuring dimensions and shapes of the FAZ before treatment of diabetic maculopathy is pointed out.

摘要

在荧光血管造影中测量了黄斑无血管区(FAZ)的面积,并对22例非增殖性糖尿病视网膜病变患者的44只眼与健康非糖尿病对照组的32只眼进行了比较。结果发现,糖尿病患者FAZ的面积平均在0.26±0.07mm²之间,而健康非糖尿病对照组为0.23±0.04mm²,差异具有统计学意义(p<0.05)。所得结果表明,由于黄斑旁毛细血管网的破坏,非增殖性视网膜病变糖尿病患者的FAZ面积明显大于健康眼,尽管健康眼中FAZ的面积可能有很大差异。文中指出了荧光血管造影在糖尿病性黄斑病变治疗前测量FAZ尺寸和形状方面的重要性。

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Graefes Arch Clin Exp Ophthalmol. 2012 Nov;250(11):1607-14. doi: 10.1007/s00417-012-2093-6. Epub 2012 Jul 4.