Bresnick G H, Condit R, Syrjala S, Palta M, Groo A, Korth K
Arch Ophthalmol. 1984 Sep;102(9):1286-93. doi: 10.1001/archopht.1984.01040031036019.
The dimensions of the foveal avascular zone (FAZ) were measured in fluorescein angiograms from 36 diabetic patients and 20 nondiabetic controls. The median values for longest diameter, mean diameter, and circumference were significantly greater in the diabetic group than in the control group. Longest diameters greater than 1.0 mm were found almost exclusively in eyes with proliferative diabetic retinopathy. The FAZ dimensions were strongly positively correlated with the severity of capillary nonperfusion in the posterior retina, but not with fluorescein leakage. The presence of proliferative diabetic retinopathy was also strongly correlated with capillary nonperfusion. Retinal capillary occlusion as the cause of FAZ enlargement in diabetic retinopathy is supported by these findings.
在36例糖尿病患者和20例非糖尿病对照者的荧光素血管造影中测量了黄斑无血管区（FAZ）的大小。糖尿病组最长径、平均直径和周长的中位数显著大于对照组。最长径大于1.0mm几乎仅见于增殖性糖尿病视网膜病变患者的眼睛。FAZ大小与视网膜后极部毛细血管无灌注的严重程度呈强正相关，但与荧光素渗漏无关。增殖性糖尿病视网膜病变的存在也与毛细血管无灌注密切相关。这些发现支持视网膜毛细血管闭塞是糖尿病视网膜病变中FAZ扩大的原因。
