Fitzgerald David M, Berecki-Gisolf Janneke, Hockey Richard L, Dobson Annette J
School of Population Health, Faculty of Health Sciences, University of Queensland, Herston, Queensland, Australia.
Menopause. 2009 Mar-Apr;16(2):279-85. doi: 10.1097/gme.0b013e3181865373.
To investigate whether overweight women are more likely to have a hysterectomy and whether hysterectomy leads to increased weight gain.
Survey data of middle-aged women participating in the Australian Longitudinal Study on Women's health in 1996 (ages 45-50 y; n = 13,125), 1998 (n = 10,612), 2001 (n = 10,293), and 2004 (n = 9309) included self-reported height, weight, and hysterectomy. First, we conducted a cohort analysis, comparing body mass index (BMI) of women categorized according to hysterectomy status. Second, we used a nested case-control analysis to compare weight gain between women who underwent hysterectomy and women who did not have a hysterectomy, matched for prehysterectomy weight, height, menopause status, and educational level.
At survey 1, the mean BMI of women who subsequently had a hysterectomy was greater than that of women without a hysterectomy by survey 2 (difference, 1.1 kg/m; 95% CI, 0.5-1.6). Results were similar for surveys 2 to 3 (BMI difference, 0.8 kg/m; 95% CI, 0.3-1.3) and surveys 3 to 4 (BMI difference, 0.8 kg/m; 95% CI, 0.1-1.4). Having a hysterectomy between surveys 1 and 2 was not associated with percentage of weight gain over the 3 or 6 years after survey 2 (odds ratio, 0.98 [95% CI, 0.96-1.01] and 0.99 [95% CI, 0.97-1.01], respectively). Having a hysterectomy between surveys 2 and 3 was weakly associated with percentage of weight gain over 3 years (odds ratio, 1.03 [95% CI, 1.00-1.05]).
Among women older than 45 to 50 years, hysterectomy did not lead to greater weight gain but was more likely to be performed in heavier women.
研究超重女性是否更易接受子宫切除术，以及子宫切除术是否会导致体重增加。
1996年（45 - 50岁；n = 13125）、1998年（n = 10612）、2001年（n = 10293）和2004年（n = 9309）参与澳大利亚女性健康纵向研究的中年女性的调查数据包括自我报告的身高、体重和子宫切除术情况。首先，我们进行了队列分析，比较根据子宫切除术状态分类的女性的体重指数（BMI）。其次，我们采用巢式病例对照分析，比较接受子宫切除术的女性和未接受子宫切除术的女性之间的体重增加情况，两组在子宫切除术前的体重、身高、绝经状态和教育水平方面进行匹配。
在第1次调查时，随后接受子宫切除术的女性的平均BMI比到第2次调查时未接受子宫切除术的女性高（差异为1.1 kg/m²；95% CI，0.5 - 1.6）。第2次到第3次调查结果相似（BMI差异为0.8 kg/m²；95% CI，0.3 - 1.3），第3次到第4次调查结果也相似（BMI差异为0.8 kg/m²；95% CI，0.1 - 1.4）。在第1次和第2次调查之间接受子宫切除术与第2次调查后3年或6年的体重增加百分比无关（比值比分别为0.98 [95% CI，0.96 - 1.01]和0.99 [95% CI，0.97 - 1.01]）。在第2次和第3次调查之间接受子宫切除术与3年的体重增加百分比有弱关联（比值比为1.03 [95% CI，1.00 - 1.05]）。
在45至50岁以上的女性中，子宫切除术不会导致体重增加更多，但超重女性更有可能接受子宫切除术。
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