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[多发性硬化症中的眼球运动障碍]

[Ocular motor disorders in multiple sclerosis].

作者信息

Rougier M-B, Tilikete C

机构信息

Unité Rétine-Uvéites-Neuro-ophtalmologie, Service d'Ophtalmologie, Hôpital Pellegrin - CHU de Bordeaux, Bordeaux, France.

出版信息

J Fr Ophtalmol. 2008 Sep;31(7):717-21. doi: 10.1016/s0181-5512(08)74390-0.

Abstract

Multiple sclerosis is the most common disabling neurological disease in young people. Many neuro-ophthalmological manifestations can occur during the course of the illness, and optic neuritis is both the most frequent and the best known. However, some ocular motility disorders can also occur, but since there may be no symptoms, they often remain underdiagnosed. These eye movement disorders are mostly related to brain-stem and cerebellum lesions. They can be acute, indicating a spatial dissemination of the demyelinating disease, and consequently may indicate the need for systemic treatment of multiple sclerosis. More often, they evolve slowly, progressing with the multiple sclerosis. In this case, they could provide a clue to the prognosis of the disease. In this survey, we discuss the two major symptoms of ocular motor disorders likely to occur during multiple sclerosis: oscillopsia and diplopia.

摘要

多发性硬化症是年轻人中最常见的致残性神经疾病。在疾病过程中可出现许多神经眼科表现,其中视神经炎最为常见且最为人所知。然而,一些眼球运动障碍也可能发生,但由于可能没有症状,它们常常未被充分诊断。这些眼球运动障碍大多与脑干和小脑病变有关。它们可以是急性的,表明脱髓鞘疾病的空间扩散,因此可能提示需要对多发性硬化症进行全身治疗。更常见的是,它们进展缓慢,随多发性硬化症一同发展。在这种情况下,它们可为疾病的预后提供线索。在本次综述中,我们讨论多发性硬化症期间可能出现的两种主要眼球运动障碍症状:视振荡和复视。

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