• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

多发性硬化症的症状管理

Symptomatic management in multiple sclerosis.

作者信息

Shah Pushkar

机构信息

Department of Neurology, Institute of Neurosciences, South Glasgow University Hospital NHS Trust, Glasgow, G51 4TF, United Kingdom.

出版信息

Ann Indian Acad Neurol. 2015 Sep;18(Suppl 1):S35-42. doi: 10.4103/0972-2327.164827.

DOI:10.4103/0972-2327.164827
PMID:26538847
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4604696/
Abstract

Multiple sclerosis (MS) is the commonest cause of disability in young adults. While there is increasing choice and better treatments available for delaying disease progression, there are still, very few, effective symptomatic treatments. For many patients such as those with primary progressive MS (PPMS) and those that inevitably become secondary progressive, symptom management is the only treatment available. MS related symptoms are complex, interrelated, and can be interdependent. It requires good understanding of the condition, a holistic multidisciplinary approach, and above all, patient education and empowerment.

摘要

多发性硬化症(MS)是年轻成年人致残的最常见原因。虽然在延缓疾病进展方面可供选择的治疗方法越来越多且越来越好,但有效的对症治疗仍然非常少。对于许多患者,如原发性进行性多发性硬化症(PPMS)患者以及那些不可避免地发展为继发性进行性多发性硬化症的患者来说,症状管理是唯一可用的治疗方法。与MS相关的症状复杂、相互关联且可能相互依存。这需要对病情有充分的了解,采用整体多学科方法,最重要的是,对患者进行教育并赋予其权力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09bc/4604696/82bf7ec844d6/AIAN-18-35-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09bc/4604696/9da5aea54e50/AIAN-18-35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09bc/4604696/82bf7ec844d6/AIAN-18-35-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09bc/4604696/9da5aea54e50/AIAN-18-35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09bc/4604696/82bf7ec844d6/AIAN-18-35-g002.jpg

相似文献

1
Symptomatic management in multiple sclerosis.多发性硬化症的症状管理
Ann Indian Acad Neurol. 2015 Sep;18(Suppl 1):S35-42. doi: 10.4103/0972-2327.164827.
2
Multiple sclerosis by phenotype in Germany.德国基于表型的多发性硬化症。
Mult Scler Relat Disord. 2022 Jan;57:103326. doi: 10.1016/j.msard.2021.103326. Epub 2021 Oct 10.
3
Treatment Patterns and Unmet Need for Patients with Progressive Multiple Sclerosis in the United States: Survey Results from 2016 to 2021.美国进行性多发性硬化症患者的治疗模式与未满足的需求:2016年至2021年的调查结果
Neurol Ther. 2023 Dec;12(6):1961-1979. doi: 10.1007/s40120-023-00532-2. Epub 2023 Sep 8.
4
Societal costs of primary progressive multiple sclerosis in Australia and the economic impact of a hypothetical disease-modifying treatment that could delay disease progression.澳大利亚原发性进行性多发性硬化症的社会成本,以及一种假设的疾病修正治疗可能延迟疾病进展的经济影响。
J Med Econ. 2021 Jan-Dec;24(1):140-149. doi: 10.1080/13696998.2021.1872585.
5
Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis.进行性阶段的发病是多发性硬化症中一个与年龄相关的临床里程碑。
Mult Scler. 2013 Feb;19(2):188-98. doi: 10.1177/1352458512451510. Epub 2012 Jun 26.
6
Ocrelizumab: A Review in Multiple Sclerosis.奥瑞珠单抗:多发性硬化症的治疗药物。
Drugs. 2022 Feb;82(3):323-334. doi: 10.1007/s40265-022-01672-9. Epub 2022 Feb 22.
7
Shared decision-making in multiple sclerosis physical symptomatic care: a systematic review.多发性硬化症身体症状护理中的共同决策:一项系统综述。
Ther Adv Chronic Dis. 2023 Jun 6;14:20406223231172920. doi: 10.1177/20406223231172920. eCollection 2023.
8
Clinical predictors of disease progression in a cohort of Tunisian progressive Multiple Sclerosis.突尼斯进展性多发性硬化队列中疾病进展的临床预测因素。
Mult Scler Relat Disord. 2021 Nov;56:103232. doi: 10.1016/j.msard.2021.103232. Epub 2021 Aug 31.
9
Summary of comprehensive systematic review: Rehabilitation in multiple sclerosis [RETIRED]: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.综合系统评价总结:多发性硬化症的康复治疗[已停用]:美国神经病学学会指南制定、传播与实施小组委员会报告
Neurology. 2015 Nov 24;85(21):1896-903. doi: 10.1212/WNL.0000000000002146.
10
Consensus recommendations for the diagnosis and treatment of primary progressive multiple sclerosis in Latin America.拉丁美洲原发性进行性多发性硬化症诊断和治疗的共识建议。
J Neurol Sci. 2018 Oct 15;393:4-13. doi: 10.1016/j.jns.2018.07.024. Epub 2018 Jul 31.

引用本文的文献

1
Primary Progressive Multiple Sclerosis: New Therapeutic Approaches.原发性进行性多发性硬化症:新的治疗方法
Neuropsychopharmacol Rep. 2025 Sep;45(3):e70039. doi: 10.1002/npr2.70039.
2
Pharmacokinetic Study of Fingolimod Nasal Films Administered via Nose-to-Brain Route in C57BL/6 J Mice as Potential Treatment for Multiple Sclerosis.经鼻脑途径给予 C57BL/6J 小鼠芬戈莫德鼻用膜的药代动力学研究,作为多发性硬化症的潜在治疗方法。
Pharm Res. 2024 Oct;41(10):1951-1963. doi: 10.1007/s11095-024-03745-8. Epub 2024 Oct 29.
3
Eyes as Windows: Unveiling Neuroinflammation in Multiple Sclerosis via Optic Neuritis and Uhthoff's Phenomenon.

本文引用的文献

1
Cognitive rehabilitation in multiple sclerosis: A systematic review.多发性硬化症的认知康复:一项系统综述。
J Neurol Sci. 2015 Jul 15;354(1-2):1-9. doi: 10.1016/j.jns.2015.05.004. Epub 2015 May 9.
2
Impact of a Pelvic Floor Training Program Among Women with Multiple Sclerosis: A Controlled Clinical Trial.盆底训练计划对多发性硬化症女性的影响:一项对照临床试验。
Am J Phys Med Rehabil. 2016 Jan;95(1):1-8. doi: 10.1097/PHM.0000000000000302.
3
Persistence of the effects of attention and executive functions intensive rehabilitation in relapsing remitting multiple sclerosis.
眼睛如窗口:通过视神经炎和乌托夫现象揭示多发性硬化症中的神经炎症
Diagnostics (Basel). 2024 Oct 2;14(19):2198. doi: 10.3390/diagnostics14192198.
4
Management of multiple sclerosis fatigue in the digital age: from assessment to treatment.数字时代多发性硬化症疲劳的管理:从评估到治疗
Front Neurosci. 2023 Oct 5;17:1231321. doi: 10.3389/fnins.2023.1231321. eCollection 2023.
5
Cellular and Molecular Evidence of Multiple Sclerosis Diagnosis and Treatment Challenges.多发性硬化症诊断与治疗挑战的细胞和分子证据
J Clin Med. 2023 Jun 26;12(13):4274. doi: 10.3390/jcm12134274.
6
Effects of behavioural therapy versus interferential current on bladder dysfunction in multiple sclerosis patients; a randomised clinical study.行为疗法与干扰电流对多发性硬化症患者膀胱功能障碍的影响;一项随机临床研究。
J Taibah Univ Med Sci. 2021 Sep 1;16(6):812-818. doi: 10.1016/j.jtumed.2021.08.003. eCollection 2021 Dec.
7
The GPR17 Receptor-A Promising Goal for Therapy and a Potential Marker of the Neurodegenerative Process in Multiple Sclerosis.GPR17 受体-A:治疗的有希望靶点和多发性硬化症神经退行性过程的潜在标志物。
Int J Mol Sci. 2020 Mar 8;21(5):1852. doi: 10.3390/ijms21051852.
8
Recent Developments in Diffusion Tensor Imaging of Brain.脑扩散张量成像的最新进展
Radiol Open J. 2015;1(1):1-12. doi: 10.17140/roj-1-101. Epub 2015 Dec 11.
9
Clinical Characteristics and Urodynamic Analysis of Urinary Dysfunction in Multiple Sclerosis.多发性硬化症患者排尿功能障碍的临床特征及尿动力学分析
Chin Med J (Engl). 2016 Mar 20;129(6):645-50. doi: 10.4103/0366-6999.177970.
注意和执行功能强化康复对复发缓解型多发性硬化症的影响的持续性
Mult Scler Relat Disord. 2012 Oct;1(4):168-73. doi: 10.1016/j.msard.2012.06.004. Epub 2012 Jul 21.
4
Sleep disorders in multiple sclerosis. Review.多发性硬化中的睡眠障碍。综述。
Curr Neurol Neurosci Rep. 2015 May;15(5):21. doi: 10.1007/s11910-015-0546-0.
5
Treatment of progressive multiple sclerosis: what works, what does not, and what is needed.进展性多发性硬化症的治疗:哪些有效,哪些无效,以及需要什么。
Lancet Neurol. 2015 Feb;14(2):194-207. doi: 10.1016/S1474-4422(14)70231-5.
6
Exercise as a therapy for improvement of walking ability in adults with multiple sclerosis: a meta-analysis.运动作为改善成年多发性硬化症患者行走能力的一种治疗方法:一项荟萃分析。
Arch Phys Med Rehabil. 2015 Jul;96(7):1339-1348.e7. doi: 10.1016/j.apmr.2015.02.011. Epub 2015 Feb 21.
7
Prevalence of dysphagia in multiple sclerosis: a systematic review and meta-analysis.多发性硬化症中吞咽困难的患病率:一项系统评价和荟萃分析。
Neurol Sci. 2015 May;36(5):671-81. doi: 10.1007/s10072-015-2067-7. Epub 2015 Feb 3.
8
Sacral nerve stimulation for faecal incontinence and constipation: a European consensus statement.骶神经刺激治疗大便失禁和便秘:欧洲共识声明。
Colorectal Dis. 2015 Apr;17(4):O74-87. doi: 10.1111/codi.12905.
9
The incidence and prevalence of psychiatric disorders in multiple sclerosis: a systematic review.多发性硬化症中心境障碍的发病率和患病率:系统评价。
Mult Scler. 2015 Mar;21(3):305-17. doi: 10.1177/1352458514564487. Epub 2015 Jan 12.
10
Vision and vision-related outcome measures in multiple sclerosis.多发性硬化症中的视力及与视力相关的预后指标
Brain. 2015 Jan;138(Pt 1):11-27. doi: 10.1093/brain/awu335. Epub 2014 Nov 28.